نتایج جستجو برای: مدل ارزیابی عمومی caf

تعداد نتایج: 247615  

Journal: :Journal of applied physiology 2011
Magni Mohr Jens Jung Nielsen Jens Bangsbo

The effect of oral caffeine ingestion on intense intermittent exercise performance and muscle interstitial ion concentrations was examined. The study consists of two studies (S1 and S2). In S1, 12 subjects completed the Yo-Yo intermittent recovery level 2 (Yo-Yo IR2) test with prior caffeine (6 mg/kg body wt; CAF) or placebo (PLA) intake. In S2, 6 subjects performed one low-intensity (20 W) and...

2008
BOKSOON MYOUNG YI DENG

This study examines the observed interannual variability of the cyclonic activity along the U.S. Pacific coast and quantifies its impact on the characteristics of both the winter total and extreme precipitation in the western United States. A cyclonic activity function (CAF) was derived from a dataset of objectively identified cyclone tracks in 27 winters (1979/80–2005/06). The leading empirica...

Journal: :Transplantation proceedings 2001
Herwig-Ulf Meier-Kriesche Bruce Kaplan

Tacrolimus and cyclosporine in the microemulsion formulation Neoral have demonstrated improvements in acute rejection rates after renal transplantation compared with conventional cyclosporine formulation, Sandimmune. To evaluate whether these drugs are also associated with improvements in chronic allograft failure (CAF) rates, we retrospectively analyzed 32,040 primary renal allograft recipient...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2013
Mercedes Herrera Abul B M M K Islam Alberto Herrera Paloma Martín Vanesa García Javier Silva Jose M Garcia Clara Salas Ignacio Casal Antonio García de Herreros Félix Bonilla Cristina Peña

PURPOSE Cancer-associated fibroblasts (CAF) actively participate in reciprocal communication with tumor cells and with other cell types in the microenvironment, contributing to a tumor-permissive neighborhood and promoting tumor progression. The aim of this study is the characterization of how CAFs from primary human colon tumors promote migration of colon cancer cells. EXPERIMENTAL DESIGN Pr...

2015
Massimiliano Migliori Vincenzo Cantaluppi Claudio Mannari Alberto A. E. Bertelli Davide Medica Alessandro Domenico Quercia Victor Navarro Alessia Scatena Luca Giovannini Luigi Biancone Vincenzo Panichi

INTRODUCTION Several studies demonstrated that endothelium dependent vasodilatation is impaired in cardiovascular and chronic kidney diseases because of oxidant stress-induced nitric oxide availability reduction. The Mediterranean diet, which is characterized by food containing phenols, was correlated with a reduced incidence of cardiovascular diseases and delayed progression toward end stage c...

2017
Nicholas Ellinwood Dobromir Dobrev Stefano Morotti Eleonora Grandi

Current pharmacological therapy against atrial fibrillation (AF), the most common cardiac arrhythmia, is limited by moderate efficacy and adverse side effects including ventricular proarrhythmia and organ toxicity. One way to circumvent the former is to target ion channels that are predominantly expressed in atria vs. ventricles, such as KV1.5, carrying the ultra-rapid delayed-rectifier K+ curr...

Journal: :The Lancet 2009
Kathy S Albain William E Barlow Peter M Ravdin William B Farrar Gary V Burton Steven J Ketchel Charles D Cobau Ellis G Levine James N Ingle Kathleen I Pritchard Allen S Lichter Daniel J Schneider Martin D Abeloff I Craig Henderson Hyman B Muss Stephanie J Green Danika Lew Robert B Livingston Silvana Martino C Kent Osborne

BACKGROUND Tamoxifen is standard adjuvant treatment for postmenopausal women with hormone-receptor-positive breast cancer. We assessed the benefit of adding chemotherapy to adjuvant tamoxifen and whether tamoxifen should be given concurrently or after chemotherapy. METHODS We undertook a phase 3, parallel, randomised trial (SWOG-8814, INT-0100) in postmenopausal women with hormone-receptor-po...

2016
Wei Guan Haiqing Liao Li Guo Changning Wang Zhengguo Cao

PURPOSE Gingival recession is a major esthetic concern and may lead to root sensitivity during periodontal treatment. Coronally advanced flaps (CAFs) with and without acellular dermal matrix (ADM) are widely used in root coverage procedures. The aim of this study was to analyze the efficacy of CAF in combination with ADM in the treatment of gingival recession. METHODS PubMed, The Cochrane Lib...

Journal: :Rapid communications in mass spectrometry : RCM 2013
Ana Butorac Ivana Dodig Višnja Bačun-Družina Arye Tishbee Jasna Mrvčić Karlo Hock Janko Diminić Mario Cindrić

RATIONALE We describe a novel negative chemically activated fragmentation/positive chemically activated fragmentation (CAF-/CAF+) technique for protein identification. The technique was used to investigate Lactobacillus brevis adaptation to nutrient deprivation. METHODS The CAF-/CAF+ method enables de novo sequencing of derivate peptides with negative and positive ion mode matrix-assisted las...

2017
Shane R. Horman Jeremy To John Lamb Jocelyn H. Zoll Nicole Leonetti Buu Tu Rita Moran Robbin Newlin John R. Walker Anthony P. Orth

Recent advances in chemotherapeutics highlight the importance of molecularly-targeted perturbagens. Although these therapies typically address dysregulated cancer cell proteins, there are increasing therapeutic modalities that take into consideration cancer cell-extrinsic factors. Targeting components of tumor stroma such as vascular or immune cells has been shown to represent an efficacious ap...

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