We report a 44-year-old female with striatonigral degeneration (SND) who showed wearing-off oscillations after 4 months of levodopa treatment. The patient presented with asymmetric left-side dominant rigidity, and levodopa was effective at first. However, she began to show wearing-off oscillations of motor symptoms, which gradually worsened thereafter. Fluid-attenuated inversion recovery sequen...

This work is mainly focused on showing experimental results using a combination of two methods for noise compensation which are shown to be complementary: classical spectral subtraction algorithm and histogram equalization. While spectral subtraction is focused on the reduction of the additive noise in the spectral domain, histogram equalization is applied in the cepstral domain to compensate t...

Step-feeding strategies have been extensively studied and comprehensively analyzed in this study for a four-stage alum sludge-based tidal flow constructed wetlands (AlS-TFCWs) system. Enhanced total nitrogen removal of 83% is achieved under high nitrogen loading rate of 19.1 g N/m(2)d. The key issues towards the success of a significant nitrogen removal in step-feeding TFCWs are the bed resting...

The first ten cycles following cessation of atrial pacing were evaluated in 44 control subjects (mean age 52.9 ± 14.88 yr) and 39 patients (mean age 62.9 ± 15.41 yr) suspected of having sinus node dysfunction (SND). The maximal cycle length for each postpacing cycle following several pacing periods in each control subject was determined, and was normalized by dividing it by the subject's mean s...

Hyperthermia is an environmental stressor that produces marked increases in visceral sympathetic nerve discharge (SND) in young rats. The brainstem in rats contains the essential neural circuitry for mediating visceral sympathetic activation; however, specific brainstem sites involved remain virtually unknown. The rostral ventral lateral medulla (RVLM) is a key central nervous system region inv...

We tested the hypothesis that central angiotensin II (ANG II) administration would activate splenic sympathetic nerve discharge (SND), which in turn would alter splenic cytokine gene expression. Experiments were completed in sinoaortic nerve-lesioned, urethane-chloralose-anesthetized, splenic nerve-intact (splenic-intact) and splenic nerve-lesioned (splenic-denervated) Sprague-Dawley rats. Sple...

INTRODUCTION Sinus node dysfunction (SND) commonly manifests with atrial arrhythmias alternating with sinus pauses and sinus bradycardia. The underlying process is thought to be because of atrial fibrosis. We assessed the value of atrial fibrosis, quantified using late gadolinium enhanced-MRI (LGE-MRI), in predicting significant SND requiring pacemaker implant. METHODS Three hundred forty-fou...

A bstract The ( g − 2) μ anomaly indicates that the second generation of leptons should have new interactions beyond standard model. high flux ν and $$ \overline{\nu} ν ¯ at forward experiments such as FASER SND@LHC makes them suitable setups to search for leptons. In...