OBJECTIVE To describe a large family with a novel mutation in CHM. METHODS Family members were characterized using clinical examination, wide-field fundus photography, wide-field autofluorescence, and spectral domain optical coherence tomography. The CHM mutation was identified with the National Institutes of Health-sponsored eyeGene program. RESULTS A novel nonsense CHM mutation (T1194G), ...

PURPOSE To describe the clinical and molecular findings of an Italian family with a new mutation in the choroideremia (CHM) gene. METHODS We performed a comprehensive ophthalmologic examination, fundus photography, macular optical coherence tomography, perimetry, electroretinography, and fluorescein angiography in an Italian family. The clinical diagnosis was supported by western blot analysi...

Background. Postpartum depression (PPD) does great harm to women following childbirth. The aim of this study was to conduct a systematic review of the literature to assess the efficacy and safety of CHM for the treatment of PPD. Methods. Published or ongoing registered trials were searched for from the inception of the various databases to December 31, 2015. Data extraction and methodology asse...

The objective of this study is to test the feasibility of nation-wide medium footprint airborne laser scanning (ALS) data for derivation of forest parameters. The comparison of canopy closure as one important parameter for many forest functions derived from ALS data and aerial photo interpretation was conducted. The present study was carried out in the framework of the Swiss National Forest Inv...

Asthma is one of the most common allergic respiratory diseases around the world and places great burden on medical payment. Chinese herbal medicine (CHM) is commonly used for Taiwanese children to control diseases. The aim of this study is to analyze the CHM prescriptions for asthmatic children by using a nationwide clinical database. The National Health Insurance Research Database (NHIRD) was ...

Chinese herbal medicine (CHM) is an integral component of complementary/alternative medicine and it is increasingly becoming the preferred therapeutic modality for the treatment of liver fibrosis and hepatocellular carcinoma (HCC) worldwide. Accordingly, the World Health Organization (WHO) has attested to the popularity and efficacy of indigenous herbal therapies including CHM as a first line o...

OBJECTIVE The aim of this study was to determine the oxidative status and antioxidative status of plasma of patients with complete hydatidiform mole (CHM) and to compare these values with normal pregnancy. METHOD Thirty-eight patients with CHM and 31 healthy pregnant women were enrolled in the study. To determine the antioxidative status of plasma, total antioxidant potential (TAOP) was calcu...

OBJECTIVE Myelosuppression is a common side effect in cancer patients receiving chemotherapy or radiotherapy. Chinese herbal medicine (CHM) has shown promise in alleviating myelosuppression. METHOD We searched for randomized controlled trials (RCTs) from seven databases without language restriction. We included RCTs in adults, in which hematological toxicity was measured according to WHO crit...

A major hurdle that humbles the modernization of traditional Chinese herbal medicine (CHM) is the inconsistency of chemical composition, which is inevitable due to the natural origins of CHM. Here I propose a concept of a new category of drugs, named "post-absorption/metabolism multicompound drug (PAMD)" that will meet every standard of modern pharmaceuticals, yet maintain the fundamental princ...

BACKGROUND Chinese herbal medicine (CHM) has been commonly used for treating osteoarthritis in Asia for centuries. This study aimed to conduct a large-scale pharmaco-epidemiologic study and evaluate the frequency and patterns of CHM used in treating osteoarthritis in Taiwan. METHODS A complete database (total 22,520,776 beneficiaries) of traditional Chinese medicine (TCM) outpatient claims of...