background: one of the major paths for drug development is the study of bioactivities of natural products. therefore, the aim of this study was to compare the cytotoxic effects of aqueous extract of whole cuscuta chinensis lam., which is a traditional medicinal herb commonly used in iran and other oriental countries, on the human caucasian acute lymphoblastic leukemia (ccrf-cem) and another hum...

Higher alcohol, as an inevitable product of fermentation, plays important role in the flavor and quality Baijiu. However, relationship between complex microbial metabolism formation higher alcohols rice-flavor Baijiu was not clear. To investigate microorganisms alcohol production, two fermentation mashes inoculated with starters from Heyuan Jinhuangtian Liquor Co., Ltd. (Heyuan, China) JM Guang...

The plasma concentration of cholesterol carried in low density lipoproteins is principally determined by the level of LDL receptor activity (Jm) and the LDL-cholesterol production rate (Jt) found in animals or man. This study delineates which saturated fatty acids alter Jm and Jt and so increase the plasma LDL-cholesterol level. Jm and Jt were measured in vivo in hamsters fed a constant level o...

Dual specificity phosphatases (DSP) play an important role in control of the cell cycle and signal transduction. We have synthesized a new class of DSP inhibitors. Cpd 5 or [2-(2-mercaptoethanol)-3-methyl-1,4-naphthoquinone] is one of the most potent of these. It inhibits DSPs of cells in culture and induces tyrosine phosphorylation of various DSP substrates, including the Cdc25 target Cdks and...