Stereocomplex poly(lactide) (PLA) was obtained by solution blending of linear PLLA and PDLA-PEG-PDLA. Effects of the L/D ratios, PEG block, and PDLA block on stereocomplexation of the blends are systemically discussed. The full stereocomplex PLA can be acquired by solution blending when L/D ratios are in the range of 7/3–5/5. The experiment results demonstrated that the stereocomplex degree of ...

Forged composites of raw particulate unsintered hydroxyapatite/poly-L-lactide (F-u-HA/PLLA) devices possess high mechanical strength, bioactivity, and radio-opacity. The aim of this study was to assess the efficacy of F-u-HA/PLLA screws in the treatment of lateral tibial condylar fractures. From January 2005 to December 2010, a total of 7 patients with displaced closed lateral tibial condylar f...

PLLA fibrous tissue scaffolds with controlled fiber nanoscale surface roughness are fabricated with a novel centrifugal jet spinning process. The centrifugal jet spinning technique is a highly efficient synthesis method for micron- to nano-sized fibers with a production rate up to 0.5 g min(-1). During the centrifugal jet spinning process, a polymer solution jet is stretched by the centrifugal ...

N, N'-oxalyl bis(piperonylic acid) dihydrazide (PAOD) was obtained through the amination of piperonylic acid chloride and its structure characterized by Fourier transform infrared spectrometer nuclear magnetic resonance. Melting blend technology used to prepare modified poly(L-lactic (PLLA) containing various loading PAOD as a new organic nucleating agent. The thermal performances including cry...

Poly(L-lactic acid)-co-bisphenol-A epoxy resin/vermiculite nanocomposites (PLLA–co-bis A ER/VMT) were prepared by in situ melt polycondensation of L-LA in the presence of amino-modified vermiculite. The fourier transform infrared (FTIR) spectra was used to investigate molecular interactions between the modified vermiculite and PLLA. Transmission electron microscopy (TEM) testing indicated that ...

Different scaffolds have been designed for ligament tissue engineering. Knitted scaffolds of poly-L-lactic acid (PLLA) yarns and co-polymeric yarns of PLLA and poly(glycolic acid) (PLGA) were characterized in the current study. The knitted scaffolds were immersed in medium for 20 weeks, before mass loss, molecular weight, pH value change in medium were tested; changes in mechanical properties w...

Development of novel biomaterials with Mg(2+), Ca(2+), and silicate ions releasability for bone regeneration is now in progress. Several inorganic ions have been reported to stimulate bone-forming cells. We featured Ca(2+), silicate, and especially, Mg(2+) ions as growth factors for osteoblasts. Various biomaterials, such as ceramic powders and organic-inorganic composites, that release the ion...

This work investigates the effect of the sequential availability of ZnO nanoparticles, (nanorods of ∼40nm) loaded within a degradable poly(lactic acid) (PLLA) matrix, in cell differentiation. The system constitutes a dynamic surface, in which nanoparticles are exposed as the polymer matrix degrades. ZnO nanoparticles were loaded into PLLA and the system was measured at different time points to ...