BACKGROUND Focal laryngeal candidiasis is not reported widely and is very infrequently recognized clinically. This disease is rare and may occur after pulmonary, pharyngeal and esophageal candidiasis or as part of disseminated disease. It is also secondary to inhaled steroid therapy which is usually mild and has been reported in 10-15 percent of patients taking these medications. CASE PRESENT...

Here, it is shown that immunoneutralization of p43, a virulence-associated immunomodulatory protein secreted by Candida albicans, is responsible for immunoprotection against candidiasis after spontaneous healing of mice inoculated with 10(6) C. albicans blastoconidia. p43 is produced by the pathogenic Candida blastoconidia, and neither immunoprotection nor immunoneutralization can be elicited b...

BACKGROUND AND OBJECTIVES Candidiasis is a common opportunistic infection in HIV-infected patients. The spectrum of Candida infection is diverse, starting from asymptomatic colonization to pathogenicforms. The low absolute CD4+ T-lymphocyte count has traditionally been cited as the greatest risk factor for the development of Oropharyngeal Candidiasis and current guidelines suggest increased ris...

Two cases of invasive candidiasis in intensive care patients are presented to illustrate the usefulness of detection of antibodies to Candida albicans germ tubes in the diagnosis of invasive candidiasis and in monitoring the efficacy of the antifungal treatment.

Objective/Methods. To determine the outcomes of invasive neonatal candidiasis before institution of routine antifungal prophylaxis, we conducted a retrospective review of cases of invasive candidiasis in newborns in a referral-based neonatal intensive care unit located in a single tertiary academic center between January 1998 and December 2002. Results. Sixty-three newborns with invasive neonat...

Because it is often difficult to diagnose invasive Candida infections, a sensitive hemagglutination inhibition assay to detect the surface antigen, mannan, was developed. Mannan antigenemia was detected early in the course of infection in 4 of 14 patients with systemic candidiasis and 2 of 5 patients with invasive gastrointestinal candidiasis. Mannan was not detected in 48 patients with noninva...

introduction: vaginits is probably the most common infection in women during their reproductive years, resulting in 5-10 million health-care visits a year, worldwide. vulvovaginal candidiasis (vvc) is the second-most common form of vaginitis in the united states, which is associated with use of oral contraceptives containing high levels of estrogen and hormonal therapies. midwives play an impor...