پژوهش حاضر با هدف تبیین چارچوب صلاحیت های حرفه ای مربیان و استادکاران آموزش فنی وحرفه ای انجام شده است. تبیین صلاحیت های حرفهای مذکور می تواند به بهبود برنامهریزی آموزشیهنرستانهای فنی و حرفهای کمک دهد. پژوهش به شیوة توصیفی از نوع تحلیل اسنادی انجام و طیآن گزارهها بهوسیله استنتاج مبتنی بر تحلیل مفاهیم و متن تحلیل شدهاند. جامعه پژوهش کلیه کتب،مقالهها و پژوهش های مرتبط با موضوع پژوهش بود که به کمک...

Two decades ago, Megiddo and Dyer showed that linear programming in 2 and 3 dimensions (and subsequently, any constant number of dimensions) can be solved in linear time. In this paper, we consider linear programming with at most k violations: finding a point inside all but at most k of n given halfspaces. We give a simple algorithm in 2-d that runs in O((n + k2) logn) expected time; this is fa...

BACKGROUND Transcription factor Oct1 regulates multiple cellular processes. It is known to be phosphorylated during the cell cycle and by stress, however the upstream kinases and downstream consequences are not well understood. One of these modified forms, phosphorylated at S335, lacks the ability to bind DNA. Other modification states besides phosphorylation have not been described. METHODOL...

Ubiquitylation of the epithelial Na+ channel (ENaC) plays a critical role in cellular functions, including transmembrane transport of Na+, Na+ and water balance, and blood pressure stabilization. Published studies have suggested that ENaC subunits are targets of ER-related degradation (ERAD) in yeast systems. However, the molecular mechanism underlying proteasome-mediated degradation of ENaC su...

The Harary-Hill conjecture, still open after more than 50 years, asserts that the crossing number of the complete graph Kn is H(n) = 1 4 ⌊ n 2 ⌋⌊ n− 1 2 ⌋⌊ n− 2 2 ⌋⌊ n− 3 2 ⌋ . Ábrego et al. [3] introduced the notion of shellability of a drawing D of Kn. They proved that if D is s-shellable for some s ≥ b 2 c, then D has at least H(n) crossings. This is the first combinatorial condition on a dr...

Molecular information theory was used to create sequence logos and promoter models for eight phages of the T7 group: T7, phiA1122, T3, phiYeO3-12, SP6, K1-5, gh-1 and K11. When these models were used to scan the corresponding genomes, a significant gap in the individual information distribution was observed between functional promoter sites and other sequences, suggesting that the models can be...

The ubiquitin fold is a versatile and widely used targeting signal that is added post-translationally to a variety of proteins. Covalent attachment of one or more ubiquitin domains results in localization of the target protein to the proteasome, the nucleus, the cytoskeleton or the endocytotic machinery. Recognition of the ubiquitin domain by a variety of enzymes and receptors is vital to the t...

The crossing number cr(G) of a graph G is the minimum number of edge crossings over all drawings of G in the Euclidean plane. The k-planar crossing number crk(G) of G is min{cr(G1) + cr(G2) + . . .+ cr(Gk)}, where the minimum is taken over all possible decompositions of G into k subgraphs G1, G2, . . . , Gk. The problem of computing the crossing number of complete graphs, cr(Kn), exactly for sm...