Two novel "turn-on" fluorescent probes with perylene tetracarboxylic diimide (PDI) as the fluorophore and two different di-(2-picolyl)-amine (DPA) groups as the metal ion receptor (PDI-1 and PDI-2) were successfully synthesized with satisfactory yields. PDI-1 exhibited high selectivity toward Ni(2+) in the presence of various other metal cations including Zn(2+), Cd(2+) and Cu(2+) which were ex...

Post-streptococcal autoimmunity affects millions worldwide, targeting multiple organs including the heart, brain, and kidneys. To explore the post-streptococcal autoimmunity spectrum, we used western blot analyses, to screen 310 sera from healthy subjects with (33%) and without (67%) markers of recent streptococcal infections [anti-Streptolysin O (ASLO) or anti-DNAse B (ADB)]. A 58 KDa protein,...

Protein disulphide isomerase (PDI) is an oxidoreductase enzyme abundant in the endoplasmic reticulum (ER). In plants, PDIs have been shown to assist the folding and deposition of seed storage proteins during the biogenesis of protein bodies in the endosperm. Cloning and characterization of the complete set of genes encoding PDI and PDI like proteins in bread wheat (Triticum aestivum cv. Chinese...

A mechanism based on the sequential absorption of two photons by the components of a redox couple has been recently proposed for catalysis of the energetically demanding reduction of aryl halides. Here, we analyze the suggested photochemical mechanism of this reaction, which employs perylenediimide (PDI) as a photocatalyst, on the basis of spectroscopic, electrochemical and electron paramagneti...

In this paper, we present the concept of Passive Distributed Indexing, a general-purpose distributed search service for mobile file sharing applications, which is based on peer-to-peer technology. The service enables resource-effective searching for files distributed across mobile devices based on simple queries. Building blocks of PDI constitute local broadcast transmission of queryand respons...

PURPOSE To investigate the perception of dignity among patients hospitalized in a psychiatric setting using the Patient Dignity Inventory (PDI), which had been first validated in oncologic field among terminally ill patients. PATIENTS AND METHODS After having modified two items, we administered the Italian version of PDI to all patients hospitalized in a public psychiatric ward (Service of Ps...

We report a comprehensive study on a newly synthesized perylenetetracarboxylic diimide (PDI) hexamer together with its corresponding monomer and dimer by means of steady-state absorption and fluorescence as well as femtosecond broadband transient absorption measurements. The structure of the PDI hexamer is nearly arranged in a 3-fold symmetry by three identical and separated dimers. This unique...

Protein disulfide isomerase (PDI), ERp5, and ERp57, among perhaps other thiol isomerases, are important for the initiation of thrombus formation. Using the laser injury thrombosis model in mice to induce in vivo arterial thrombus formation, it was shown that thrombus formation is associated with PDI secretion by platelets, that inhibition of PDI blocked platelet thrombus formation and fibrin ge...

We have cloned, sequenced, and expressed full length cDNA clones encoding two abundant, luminal endoplasmic reticulum proteins (ERp), ERp59/PDI and ERp72. ERp59/PDI has been identified as the microsomal enzyme protein disulfide isomerase (PDI). An analysis of the amino acid sequence of ERp72 showed that it shared sequence identity with ERp59/PDI at three discrete regions, having three copies of...

Power Doppler imaging (PDI) has been shown to be influenced by the wall filter when assessing arterial stenoses. Real-time 3-D Doppler imaging may likely become a widespread practice in the near future, but how the wall filter could affect PDI during the cardiac cycle has not been investigated. The objective of the study was to demonstrate that the wall filter may produce unexpected major signa...