Polyamines are essential for cell proliferation; therefore, we hypothesized that arginase I or arginase II activities, via production of ornithine for polyamine synthesis, may be limiting for proliferation of endothelial cells (EC). Bovine coronary venular EC stably transfected with a lacZ gene (lacZ-EC, control), rat arginase I cDNA (AI-EC), or mouse arginase II cDNA (AII-EC) were utilized to ...

The coupling of two s-wave superconductors through a small magnetic dot is discussed. Assuming that the dot charging energy is small compared to the superconducting gap, Ec D, and that the moment of the dot is classical, we develop a simple theory of transport through the dot. The presence of the magnetic dot will position Andreev bound states within the superconducting gap at energies tunable ...

Lattice tests are quality measures for assessing the intrinsic structure of pseudorandom number generators. Recently a new lattice test has been introduced by Niederreiter and Winterhof. In this paper, we present a general inequality that is satisfied by any periodic sequence. Then, we analyze the behavior of the linear congruential generators on elliptic curves (abbr. EC-LCG) under this new la...

This paper proposes a modal logic reconstruction of temporal reasoning about partially ordered events in a logic programming framework. It considers two variants of Kowalski and Sergot's Event Calculus (EC): the Skeptical EC (SKEC) and the Credulous EC (CREC). In the presence of partially ordered sequences of events, SKEC and CREC derive the maximal validity intervals over which the relevant pr...

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Endothelial cells (EC) metabolize L-arginine mainly by arginase, which exists as two distinct isoforms, arginase I and II. To understand the roles of arginase isoforms in EC arginine metabolism, bovine coronary venular EC were stably transfected with the Escherichia coli lacZ gene (lacZ-EC, control), rat arginase I cDNA (AI-EC), or mouse arginase II cDNA (AII-EC). Western blots and enzymatic as...

OBJECTIVE Extracellular superoxide dismutase (EC-SOD) is a secreted antioxidant enzyme that binds to the outer plasma membrane and extracellular matrix through its heparin-binding domain (HBD). Carriers of a common genetic variant of EC-SOD (EC-SOD(R213G), within the HBD) have higher plasma concentration of EC-SOD and increased risk for vascular disease. In the present study, we used confocal f...