P-glycoprotein (Pgp), a member of the adenosine triphosphate-binding cassette (ABC) transporter superfamily, is a major drug efflux pump expressed in normal tissues, and is overexpressed in many human cancers. Overexpression of Pgp results in reduced intracellular drug concentration and cytotoxicity of chemotherapeutic drugs and is thought to contribute to multidrug resistance of cancer cells. ...

Lionfish (Pterois volitans), venomous predators from the Indo-Pacific, are recent invaders of the Caribbean Basin and southeastern coast of North America. Quantification of invasive lionfish abundances, along with potentially important physical and biological environmental characteristics, permitted inferences about the invasion process of reefs on the island of San Salvador in the Bahamas. Env...

Phytoplankton cell size structure strongly determines food webs, carbon pathways and energy flows, consequently moderating ecosystem functioning (Legendre & rASSouLzAdegAn, 1995; MArAÑón, 2009). It is generally accepted that in conditions when nutrients are sufficiently This work describes the dynamics of the autotrophic plankton community in Lim Bay in the north-eastern part of the Adriatic Se...

Genetic diversity within key species can play an important role in the functioning of entire communities. However, the extent to which different dimensions of diversity (e.g., the number of genotypes vs. the extent of genetic differentiation among those genotypes) best predicts functioning is unknown and may yield clues into the different mechanisms underlying diversity effects. We explicitly t...

Caldicellulosiruptor saccharolyticus is an extremely thermophilic, gram-positive anaerobe which ferments cellulose-, hemicellulose- and pectin-containing biomass to acetate, CO(2), and hydrogen. Its broad substrate range, high hydrogen-producing capacity, and ability to coutilize glucose and xylose make this bacterium an attractive candidate for microbial bioenergy production. Here, the complet...

The course of environmental conditions and shelf macrobenthic communities off Central Chile ( 361S) during the strong 1997–98 El Niño (EN) event is compared with a subsequent and basically ‘‘normal’’ period (2002–2003). Changes in macrofaunal community, feeding mode structure, and biomass size spectra are contrasted over time with changes in oceanographic and sediment settings, in order to asse...

Seasonal abundance and distribution of hypogeous fungi associated with selected stands of ponderosa pine on the Coconino and Kaibab Plateaus, Arizona, were examined using a new method that reduced the time and area needed to sample nonrandomly dispersed fungal sporocarps. As measured monthly over three years, peak sporocarp production occurred both spring and fall with the greatest species rich...

Bacterial abundance, biomass, cell volume, and morphological diversity were studied in sediment samples collected from the coastal area of the eastern mid Adriatic Sea. Samples from the topmost 10 cm of sediment were taken monthly from January to December 2002. The number of bacteria varied from 3.54 x 109 cells g–1 in July to 8.08 x 109 cells g–1 in September. Biomass was lowest in May (78 μg ...

The present paper is an attempt to test the applicability of the trophic state index (TRIX) for scaling the eutrophication along the Bulgarian Black Sea coastal zone in concert with a number of chemical and biological descriptors aimed at selection of relevant indicators of marine coastal area ecological quality. The following environmental parameters have been considered: t(o), salinity, nutri...