With the current phenomenon of aging populations in most parts of the world, there are corresponding increases in age-related conditions associated with impaired cognitive status, such as dementia and delirium. Cognitive status is a key component in carrying out activities of daily living such as walking and bathing, and departures from normal cognitive status may be indicators of acute (e.g., ...

Although most philosophical accounts about model/world relations focus on structural mappings such as isomorphism, similarity has long been discussed as an alternative account. Despite its attractions, proponents of the similarity view have not provided detailed accounts of what it means that a model is similar to a realworld target system. This article gives the outlines of such an account, dr...

to the editor; tramadol, a synthetic opioid is mainly used to treat acute and chronic pain. although this drug is not an over-the-counter medication, it has been illicitly accessible to and abused by opium addicts (1-3). studies showed excessive and widespread use of tramadol in iran (1-4). tramadol may cause constipation, drowsiness, tachycardia and respiratory distress, while the most severe ...

Dit proefschrift is goedgekeurd door de promotoren en de samenstelling van de pro-motiecommissie is als volgt: voorzitter: prof. dr. ir. Het onderzoek of ontwerp dat in dit proefschrift wordt beschreven is uitgevoerd in overeenstemming met de TU/e Gedragscode Wetenschapsbeoefening.

Playfulness came into education at a later date. There are two main theoretical paradigms around play and both are relevant to a discussion around serious games for education. Modern theories aim to mainly describe the benefits of play, and classical theories tend to focus on the reasons for play. The classical theories include explanations for children needing play like ‘surplus energy’, [4] a...

It has long been a tradition in interaction design to involve users in order to better capture user needs and preferences. The involvement of children as informants and design partners is well documented for interaction design but its use in serious games design is much less reported. Where children are contributing to the design of learning materials their knowledge may be incomplete. This pap...

A new breed of networking applications offers scientists much more than typical social networking sites, but how useful are they? Amy Maxmen reports.

An 82-year-old man with dementia presented to his primary care physician with a chief complaint of left eye swelling for 2 days. He was prescribed ciprofloxacin ophthalmic drops. A few days later, his symptoms had not improved, and he presented to the emergency department at an outside hospital with ongoing eye pain. He had loss of vision in his left eye. He noted that he may have fallen approx...