نتایج جستجو برای: زئولیت 4a
تعداد نتایج: 7446 فیلتر نتایج به سال:
p-Hydroxyphenylacetate hydroxylase (HPAH) from Acinetobacter baumannii catalyzes the hydroxylation of p-hydroxyphenylacetate (HPA) to form 3,4-dihydroxyphenylacetate (DHPA). The enzyme system is composed of two proteins: an FMN reductase (C1) and an oxygenase that uses FMNH- (C2). We report detailed transient kinetics studies at 4 degrees C of the reaction mechanism of C2.C2 binds rapidly and t...
Future treatments for chronic hepatitis C virus (HCV) infection are likely to include agents that target viral components directly. Here, the preclinical characteristics of ITMN-191, a peptidomimetic inhibitor of the NS3/4A protease of HCV, are described. ITMN-191 inhibited a reference genotype 1 NS3/4A protein in a time-dependent fashion, a hallmark of an inhibitor with a two-step binding mech...
به منظور بررسی اثر زئولیت و بنتونیت استان قم بر عملکرد و صفات لاشه جوجه های گوشتی، آزمایشی در قالب طرح کاملا تصادفی با 9 تیمار و 4 تکرار، شامل 36 واحد آزمایشی که در هر یک 20 قطعه جوجه قرار داشت، انجام شد. جوجه های گوشتی نر یک روزه، هفته اول پرورش را در یک گروه واحد گذرانده و سپس به قفس های آزمایشی تخصیص یافتند و پرورش آن ها تا 42 روزگی ادامه یافت. تیمار 1 جیره فاقد زئولیت و بنتونیت (شاهد)، تیما...
به منظور بررسی تاثیر مقادیر نیتروژن و زئولیت بر صفات زراعی گیاه کلزا در شرایط تنش خشکی، آزمایشی به صورت فاکتوریل در قالب طرح بلوک های کامل تصادفی با 3 تکرار در سال زراعی 89-1388در مزرعه پژوهشی دانشگاه آزاد اسلامی واحد تاکستان اجرا شد که در آن عامل آبیاری در دو سطح شامل آبیاری معمول (شاهد) و قطع آبیاری از مرحله گل دهی به بعد، عامل زئولیت در سه سطح عدم کاربرد و مصرف 5 و 10 تن د...
Eukaryotic initiation factor 4A (eIF-4A) is one of the factors required for the binding of mRNA to 40S ribosomal subunits (1). Nielsen et al. have reported a mouse eIF-4A cDNA encoding a protein of 390 arnino acid residues (2). Subsequently they have cloned two genes encoding eIF-4A variants (eIF-4AI and eIF-4AII) whose arnino acid sequences are 91% identical (3). The genes encoding the two pro...
Here we lay the ground work for the detection of hepatitis C viral NS3-4A protease exploiting peptide-protein interaction. The NS3-4A protease is inhibited by N-terminal cleavage products. Our approach is based on the formation of a self-assembled monolayer (SAM) of a ferrocene amino acid derivative on an electrode surface. A short NS3-4A specific inhibitory peptide (Asp-Glu-Ile-Val-Pro-Nva) wa...
The development of targeted tyrosine kinase inhibitors (TKIs) has succeeded in altering the course of chronic myeloid leukemia (CML). However, a number of patients have failed to respond or experienced disease relapse following TKI treatment. Proviral integration site for moloney murine leukemia virus‑1 (PIM‑1) is a serine/threonine kinase that participates in regulating apoptosis, cell cycle, ...
The role of the hepatitis C virus (HCV) NS3/4A protease in ablating the signaling pathway involved in the production of alpha/beta interferon (IFN-α/β) suggests a relationship between NS3/4A proteolytic activity and a patient's response to IFN-based therapy. To identify viral factors associated with the HCV treatment response, we analyzed the pretreatment NS3/4A protease gene quasispecies compo...
In this study, we present the design, synthesis, characterization and biological evaluation of structurally new ferrocenyl and ruthenocenyl derivatives of the organic anthelmintic monepantel (Zolvix®). All seven metallocenyl derivatives prepared (4a/b, 5a/b, 6a/b and 7) were isolated as racemates and characterized by 1H, 13C and 19F NMR spectroscopies, mass spectrometry, IR spectroscopy and ele...
Secondary sulfonamides (4a-8h) incorporating acetoxybenzamide, triacetoxybenzamide, hydroxybenzamide, and trihydroxybenzamide and possessing thiazole, pyrimidine, pyridine, isoxazole and thiadiazole groups were synthesized. Lactoperoxidase (LPO, E.C.1.11.1.7), as a natural antibacterial agent, is a peroxidase enzyme secreted from salivary, mammary, and other mucosal glands. In the present study...
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