Motivated by the 3.2σ(1.4σ) deviations between the recent experimental value for AFB(Rb) and the standard model(SM) prediction, we examine the effect of new physics(NP) on the Zbb̄ couplings g L and g b R. First we focus our attention on the dynamical models. Then, using effective lagrangean techniques, we discuss the corrections of NP to g L and g b R. We find some kinds of NP might explain the...

Correspondence: A. Martín-Noya, M.D., Servicio de Hematología, Hospital Universitario Virgen del Rocío, Avda. Manuel Siurot s/n1, 41013 Seville, Spain. Phone: international +34-95-4248122 – Fax: international +34-954248124 – E-mail: [email protected] A71-year-old woman was admitted to hospital because of repeated episodes of epistaxis and an eight month history of fatigue and weight loss. On ph...

The internal layering and provenance of feldspar in 3 tills and in one outwash deposit at Gahanna, Ohio, were studied by determining pebble lithologies and Rb-Sr dates of feldspar. Variations in lithology of pebbles and in the Rb-Sr ratios of feldspar in the 125—250 micrometer fractions reveal discontinuities which divide the upper 2 tills into 2 subunits each. Each of the lower subunits appear...

The tumor suppressors Retinoblastoma (Rb) and p53 are frequently inactivated in liver diseases, such as hepatocellular carcinomas (HCC) or infections with Hepatitis B or C viruses. Here, we discovered a novel role for Rb and p53 in xenobiotic metabolism, which represent a key function of the liver for metabolizing therapeutic drugs or toxins. We demonstrate that Rb and p53 cooperate to metaboli...

leptin is secreted mainly by fat, which is involved in energy metabolism and reproduction. leptin and itsreceptor (ob-r) have been detected in human spermatozoa and testis, thus it can be concluded leptin involves in male physiology. the goal of this study was determination of the presence of leptin receptor mrna in the ram testis, epididymis and spermatozoa by reverse transcription polymerase ...

B-1 lymphocytes represent a distinct B cell subset with characteristic features that include self-renewing capacity and unusual mitogenic responses. B-1 cells differ from conventional B cells in terms of the consequences of phorbol ester treatment: B-1 cells rapidly enter S phase in response to phorbol ester alone, whereas B-2 cells require a calcium ionophore in addition to phorbol ester to tr...

Allelic loss at nonrandom chromosomal sites is thought to mark the position of tumor suppressor genes involved in the pathogenesis and progression of human malignancies. Solid tumors in particular have been found to harbor multiple genetic changes resulting in loss of function mutations. Tumor suppressor genes have also been found to be involved in the progression of lymphoid tumors. Previous r...

The pl6INK4a/MTS1 (p16) gene encodes a specific inhibitor of cyclin-dependent kinase (CDK)4 and CDK6. The p16 gene is frequently mutated or deleted in many types of cancer cell lines as well as in certain types of primary tumors. p16 knockout mice are viable but predisposed to sarcoma and B-cell lymphoma. To investigate the role of p16 in human soft-tissue sarcoma tumor progression, we examined...

introduction: the treatment of cutaneous leishmaniasis (cl) is based primarily on the use of pentavalent antimonials, which may lead to many side effects limiting their use. photodynamic therapy (pdt) is an alternative for the treatment of cl, and some xanthene dyes have the potential for use in pdt. methods: the xanthenes rose bengal b (rb) and its derivatives rose bengal methyl ester (rbmet),...