Next generation image compression system should be optimized the way human vision system (HVS) works. HVS has been evolved over millions of years for the images which exist in our environment. This idea is reinforced by the fact that sparse codes extracted from natural images resemble the primary visual cortex of HVS. We have introduced a novel technique in which basis functions trained by Inde...

All known DNA tumor viruses are known to target and inactivate two main cell cycle regulatory proteins, retinoblastoma protein (pRb) and p53. Inactivation of pRb promotes host cell cycle progression into S phase, and inactivation of p53 promotes cell immortalization. The DNA tumor virus Kaposi's sarcoma associated herpesvirus (KSHV)-encoded latency-associated nuclear antigen (LANA) was shown to...

In humans, a well-developed serotonin system is localized to the pancreatic islets while being absent in exocrine pancreas. Assessment of pancreatic serotonin biosynthesis could therefore be used to estimate the human endocrine pancreas. Proof of concept was tested in a prospective clinical trial by comparisons of type 1 diabetic (T1D) patients, with extensive reduction of β-cells, with healthy...

A general exact weak solution to the nonlinear equation of conservation absolute vorticity in a thin layer an incompressible medium on rotating sphere is proposed. It takes into account helicity point vortices and non-uniformity depth layer. This used develop model observed interactions spiral atmospheric vortices. The fusion two helical (HVs) considered. We also analyze prognostic applicabilit...

Assessing greenhouse gas (GHG) emissions produced from electric vehicles (EVs) and hydrogen (HVs) requires understanding of the carbon intensity electricity generation. Without decarbonisation generation, environmental benefits low emission (LEVs) will be diminished. The UK aims to produce net zero by phasing out banning sale new conventionally fuelled (CFVs) 2035 in favour LEVs. A comparison U...

This paper investigates cooperative adaptive cruise control (CACC) for mixed platoons consisting of both human-driven vehicles (HVs) and automated (AVs). research is critical because the penetration rate AVs in transportation system will remain unsaturated a long time. Uncertainties randomness are prevalent human driving behaviours highly affect platoon safety stability, which need to be consid...

The modifications to the vaginal habitat accompanying a change to vaginal flora in bacterial vaginosis (BV) are poorly understood. In this study enzymes involved in mucin degradation were measured, including a novel glycosulfatase assay. Women attending an emergency walk-in sexually transmitted disease clinic were studied. One high vaginal swab (HVS) was used to prepare a gram-stained smear to ...

Context. Hyper-velocity stars are suggested to originate from the dynamical interaction of binary stars with the supermassive black hole in the Galactic centre (GC), which accelerates one component of the binary to beyond the Galactic escape velocity. Aims. The evolutionary status and GC origin of the hyper-velocity star SDSS J113312.12+010824.9 (aka HVS 7) is constrained from a detailed study ...

BACKGROUND Pathogenesis in non-alcoholic steatohepatitis (NASH) involves abnormal cholesterol metabolism and hepatic accumulation of toxic free cholesterol. Apical sodium-dependent bile acid transporter (ASBT) inhibition in the terminal ileum may facilitate removal of free cholesterol from the liver by reducing recirculation of bile acids (BAs) to the liver, thereby stimulating new BA synthesis...