نتایج جستجو برای: روغن سویای اپوکسی دارشده eso
تعداد نتایج: 12646 فیلتر نتایج به سال:
There is increasing evidence showing the involvement of CD4(+) T cells in initiating and maintaining antitumor immune responses. NY-ESO-1 is expressed by various tumors but not normal tissues except testis. We conducted a cancer clinical trial by using full-length NY-ESO-1 protein formulated with ISCOMATRIX adjuvant and injected into patients intramuscularly. Autologous dendritic cells pulsed w...
Purpose:We initially observed that the presence of circulating NY-ESO-1– and/or Melan-A–specific T cells in patients with stage IV melanoma was significantly associated with prolonged survival. Here, we report the ways in which the phenotypes and functions of these T cells differentially affect survival in patients preselected for NY-ESO-1 and/or Melan-A reactivity. Experimental Design: We assa...
هدف از این مطالعه بررسی اثرات فرآوری دانه سویا بر عملکرد و نیتروژن اوره ای شیر بود. در این مطالعه از هشت راس گاو شیری نژاد هلشتاین با میانگین تولید شیر 3 ± 40 کیلوگرم در روز استفاده شد. تیمار ها شامل جایگزینی سویای فرآوری شده با کنجاله سویا بود. تیمار ها اثری بر تولید شیر، ترکیبات آن نداشتند (05/0p > ). قابلیت هضم ماده خشک (006/0 = p) و ماده آلی (007/0 =p ) بین تیمار ها معنی دار بود. تیمار ها ب...
BACKGROUND Cancer/testis antigens (CTAs) are expressed in several cancers and during normal adult male germ cell differentiation. Little is known about their role in fetal development of human germ cells. METHODS We examined expression of the CTAs MAGE-A1, GAGE and NY-ESO-1 in fetal gonads by single and double immunohistochemical staining. RESULTS We found that GAGE was expressed in the pri...
Cancer testis antigens (CTAs) are promising cancer associated antigens in solid tumors, but in acute myeloid leukemia, dense promoter methylation silences their expression. Leukemia cell lines exposed to HMAs induce expression of CTAs. We hypothesized that AML patients treated with standard of care decitabine (20mg/m2 per day for 10 days) would demonstrate induced expression of CTAs. Peripheral...
BACKGROUND Adoptive T cell therapy represents an attractive modality for the treatment of patients with cancer. Peripheral blood mononuclear cells have been used as a source of antigen specific T cells but the very low frequency of T cells recognizing commonly expressed antigens such as NY-ESO-1 limit the applicability of this approach to other solid tumors. To overcome this, we tested a strate...
The programmed death 1 (PD-1) receptor is a negative regulator of activated T cells and is up-regulated on exhausted virus-specific CD8(+) T cells in chronically infected mice and humans. Programmed death ligand 1 (PD-L1) is expressed by multiple tumors, and its interaction with PD-1 resulted in tumor escape in experimental models. To investigate the role of PD-1 in impairing spontaneous tumor ...
The Cancer/Testis (CT) antigen family of genes are transcriptionally repressed in most human tissues but are atypically re-expressed in many malignant tumour types. Their restricted expression profile makes CT antigens ideal targets for cancer immunotherapy. As little is known about whether CT antigens may be regulated by post-translational processing, we investigated the mechanisms governing d...
در سالهای اخیر استفاده از ضد اکسایندههای سنتزی به علت سمّی و سرطانزابودن محدود شده است. بنابراین استفاده از منابع طبیعی به عنوان جایگزین ترکیبهای سنتزی اهمیت ویژهای دارد. در این پژوهش، تأثیر فعالیت ضد اکسایشی سطوح گوناگون اسانس دانۀ رازیانه شامل غلظتهای 1/0، 2/0، 3/0، 4/0، 5/0، 6/0، 7/0، و 8/0 میلیگرم در میلیلیتر روغن سویای تصفیه شدۀ عاری از ضد اکساینده، در دمای 90 درجۀ سلسیوس، به مدت چ...
BACKGROUND Approximately 80% of acquired eso-tracheal or mediastinal fistulae are of malignant nature. The occurrence of an eso-respiratory malignant fistula is a devastating complication for both patient and doctor, and, if not treated, records a survival time of 1 to 6 weeks. MATHERIAL AND METHOD We present a patient, aged 51, smoker,with progressive dysphagia, at first to solids, then to s...
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