Synaptic plasma membranes (SPM) and myelin were prepared from mouse brain and their physical properties evaluated by fluorescence probes. 1,6,-Diphenyl-1,3,5-hexatriene (DPH) was used as a probe of the membrane core and endogenous tryptophan as a probe of membrane proteins. In vitro addition of pentobarbital or ethanol decreased the fluorescence polarization of DPH in SPM. These decreases were ...

INTRODUCTION Pooling of multicenter brain imaging data is a trend in studies on ageing related brain diseases. This poses challenges to MR-based brain segmentation. The performance across different field strengths of three widely used automated methods for brain volume measurements was assessed in the present study. METHODS Ten subjects (mean age: 64 years) were scanned on 1.5T and 3T MRI on ...

The computerized brain atlas (CBA) and statistical parametric mapping (SPM) are two procedures for voxel-based statistical evaluation of PET activation studies. Each includes spatial standardization of image volumes, computation of a statistic, and evaluation of its significance. In addition, smoothing and correcting for differences of global means are commonly performed in SPM before statistic...

The few studies that have examined rates of acute myeloid leukemia (AML) transformation in lenalidomide-treated myelodysplastic syndrome (MDS) patients have been limited to deletion 5q MDS. The association between lenalidomide and subsequent primary malignancies (SPMs) in MDS patients has not been evaluated previously. We conducted a retrospective cohort study to evaluate the risk of both SPM a...

Cyber-physical systems and hard real-time systems have strict timing constraints that specify deadlines until which tasks must finish their execution. Missing a deadline can cause unexpected outcome or endanger human lives in safety-critical applications, such as automotive or aeronautical systems. It is, therefore, of utmost importance to obtain and optimize a safe upper bound of each task’s e...

Software Programmable Memories, or SPMs, are raw on-chip memories that are not implicitly managed by the processor hardware, but explicitly by software. For example, while caches fetch data from memories automatically and maintain coherence with other caches, SPMs explicitly manage data movement between memories and other SPMs through software instructions. SPMs make the design of on-chip memor...

A hydro-optical algorithm based on reflectance at 555nm has been used in the past for suspended particulate matter concentrations (SPM) retrieval from SeaWiFS over the Belgian coastal (case II) waters in Southern North Sea. The extra spectral resolution of MERIS offers the possibility of improvements, though necessitates algorithm recalibration. This study presents the calibration of the hydro-...

This paper develops and tests a privacy-preserving business process that supports the selection of a contract manufacturer by an original equipment manufacturer (OEM), and the determination of whether the OEM or the chosen contract manufacturer will procure each of the components to be used in the manufacture of the OEM’s branded product. Our ‘‘secure price-masking (SPM)’’ technology contribute...

22 23 Polyamines are absolute requirements for cell growth. When in excess, P. aeruginosa possesses 24 six γ-glutamylpolyamine synthetases (GPSs) encoded by the pauA1-pauA7 genes to initiate 25 polyamine catabolism. Recently, the pauA2 mutant was reported to lose the capability to grow on 26 spermine (Spm) and spermidine (Spd) as sole carbon and nitrogen sources. Although this mutant 27 grew no...

Ocean color satellite sensors are powerful tools to study and monitor the dynamics of suspended particulate matter (SPM) discharged by rivers in coastal waters. In this study, we test the capabilities of Landsat-8/Operational Land Imager (OLI), AQUA&TERRA/Moderate Resolution Imaging Spectroradiometer (MODIS) and MSG-3/Spinning Enhanced Visible and Infrared Imager (SEVIRI) sensors in terms of sp...