Parallel interference cancellation (PIC) principle is conceptually simple and yet eeective method of parameter estimation and data detection in the presence of multiple-access and multipath interference. It uniies some of the known methods of data detection, complex channel co-eecient estimation, as well as delay tracking in DS-CDMA receivers. The PIC method will be derived and some numerical r...

Transcription by all three eukaryotic RNA polymerases involves the assembly of a large preinitiation complex (PIC) at gene promoters. The PIC comprises several general transcription factors (GTFs), including TBP, and the respective RNA polymerase. It has been suggested that some GTFs remain stably bound at active promoters to facilitate multiple transcription events. Here we used two complement...

The current paradigm of cosmic ray (CR) origin states that the most part galactic CRs is produced by supernova remnants. interaction ejecta with interstellar medium after supernova's explosions results in shocks responsible for CR acceleration via diffusive shock (DSA). We use particle-in-cell (PIC) simulations and a combined PIC-magnetohydrodynamic (PIC-MHD) technique to investigate whether DS...

The aim of this thesis is to investigate practical multiuser demodulation algorithms for mobile communications systems that are based on code division multiple access ( C D M A ) technologies. These include the adaptive receiver and the interference canceller. The overall complexity of implementing them is examined. The effects of the proposed algorithms on reducing of multiple access interfere...

The presence of phosphoinositide-mobilizing enzymes has been investigated in purified rat liver nuclei by radiolabelling and by probing with antibodies. A Ca(2+)-activated phosphoinositidase C (PIC) is present and was shown immunologically to be the beta 1 isoform. No gamma- or delta-PIC was found. However, only 5% of the total beta 1-PIC isoform is nuclear, with the majority being cytosolic. G...

The effect of humidity treatments on the surface morphology of spin-coated pseudoisocyanine (PIC) dye films on mica was investigated by absorption spectroscopy, fluorescence microscopy, and atomic force microscopy (AFM). We demonstrated that the humidity treatment caused dynamic changes of mesoscopic J aggregate morphology due to the mobile nature of PIC molecules on mica surface. Under dry con...

The protein density and arrangement of subunits of a complete, 32-protein, RNA polymerase II (pol II) transcription pre-initiation complex (PIC) were determined by means of cryogenic electron microscopy and a combination of chemical cross-linking and mass spectrometry. The PIC showed a marked division in two parts, one containing all the general transcription factors (GTFs) and the other pol II...

Whereas individual RNA polymerase II (pol II)-general transcription factor (GTF) complexes are unstable, an assembly of pol II with six GTFs and promoter DNA could be isolated in abundant homogeneous form. The resulting complete pol II transcription preinitiation complex (PIC) contained equimolar amounts of all 31 protein components. An intermediate in assembly, consisting of four GTFs and prom...

The phosphate carrier (PiC) catalyses the import of phosphate into mitochondria where it is needed for ATP synthesis. We have analysed the 5'-flanking region of the human PiC gene and found that it has a single transcriptional initiation site and lacks a TATA box. Through deletion analysis of the -1213/-25 nt region, we identified an activation domain (-223/-25) and an inhibition domain (-1017/...