objective(s):parkinson's disease (pd) is known for motor impairments. but often, there are non-motor symptoms such as cognitive deficiency and pain misperception, owing to possible role of nigrostriatal pathway. antioxidants have protective effect on free radical-induced neuronal damage in pd. to further address, we examined the effects of ellagic acid (ea) in a rat model of pd induced by ...

abstract   background: multiple sclerosis (ms) is the most common autoimmune disease of central nervous system with destruction of myelin sheath mediated by auto reactive cd4+ t lymphocytes. because of the possible role of epstein-barr virus in etiology of ms and t cells immune response, the aim of this study was to evaluate anti-epstein barr virus antibodies as a marker of reactivity and produ...

background & aim: artemisia species with common persian name of dermaneh are found all over iran and are used for treatment in infectious diseases such as malaria, hepatitis and other diseases. some artemisia species are used in traditionally as tonic and anti-helmintic in north of iran. artemisia haussknechtii is used in dyspepsia and other gastrointestinal disorders by local people in the wes...

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evidences indicate that angiogenesis  is an important process in the development of destructive synovial tissue in rheumatoid  arthritis (ra). recently, it has been shown that the polymorphism of the integrin-αv subunit encoded by the itgav gene plays a role in angiogenesis and is considered  as ra susceptibility loci. this study investigated association of four single nucleotide polymorphisms ...

objective: periapical granulomas (pgs) and radicular cysts (rcs), as the most common odontogenic lesions have yet unclear pathogenesis. this study was aimed to compare pcna and ki-67 expression in pgs and rcs and evaluate their possible relationship with two lesions. methods: in this cross-sectional descriptive study, twenty pgs and twenty rcs were evaluated immunohistochemically using an anti-...

abstract: salicylic acid is a phytohormone with phenolic nature which has been proved its role in increasing plant resistance to biotic and abiotic stress in several studies. this study was performed in order to investigation of interaction between 0, 0.5 and 1.5 mm concentrations of salicylic acid, as a seed pretreatment and different levels of drought stress (100, 75, 50 and 25 percent of fie...

1,3-dipolar cycloaddition reaction of 1 mol or 2 mol of dibenzalaceton with 1 mol of non-stabilized azomethinylides generated in situ by decarboxylative condensation of isatin and proline or sarcosine give the novel new spiro-oxindolo(pyrrolizidines/ pyrrolidines) instead of bis-spirooxindolo( pyrrolizidines/ pyrrolidines).

sulfonic acid functionalized sba-15 (sba-pr-so3h) as a new nanoporous acid catalyst was used in the one-pot synthesis of polyhydroquinolines derivatives via the hantzsch four component condensation reaction of aldehydes, b-ketoesters, dimedone and ammonium acetate under solvent free conditions with short reaction time in excellent yields. sba-pr-so3h was proved to be an efficient heterogeneous ...