Food allergy can influence the development of colorectal cancer, although the underlying mechanisms are unclear. While mast cells (MC) store and secrete histamine, immature myeloid cells (IMC) are the major site of histidine decarboxylase (HDC) expression, the enzyme responsible for histamine production. From our earlier work, we hypothesized that histamine is central to the association between...

BACKGROUND The neurosurgical procedure of hinge decompressive craniectomy (hDC), or hinge craniotomy (HC), as described from units in the advanced countries makes use of metallic implants, usually titanium plates and screws, which may not be economically viable in resource-limited practice settings. METHODS We describe our surgical techniques for performing this same procedure of hDC in a dev...

OBJECTIVE The goal was to explore the association of being underinsured and receiving doses at a health department clinic (HDC) with not receiving all recommended adolescent vaccine doses. METHODS A total of 5657 adolescents, 13 to 17 years of age, were sampled in the National Immunization Survey-Teen in 2006-2007. RESULTS A total of 63.9% of all adolescents were covered by private health i...

Immunoglobulin (Ig)E-mediated activation of mast cells has long been thought to occur only when Fc(epsilon)RI receptor-bound IgE is cross-linked via multivalent antigens. However, recent studies have raised the possibility that mast cells may be activated by the binding of IgE to the Fc(epsilon)RI receptor in the absence of antigen. Here we demonstrate that IgE binding without antigen induces t...

In previous studies we found that anionic surfactants such as sodium laurate (SL) and/or sodium dodecylsulfate (SDS) exert actions on epidermal keratinocytes rather than mast cells to give rise of histamine production and skin itching through increasing the expression of the 53-kDa active form of L-histidine decarboxylase (HDC). In addition, with treatment of SL in a three-dimensional human ker...

threatening diseases often inspire hope, patient demand, and physician enthusiasm before evaluation. In the late 1980s, highdose chemotherapy/autologous bone marrow transplantation (HDC/ABMT) emerged as a promising medical procedure for treating metastatic and high-risk breast cancer. But procedures, unlike new drugs, face no requirement for evaluation by randomized clinical trials (RCTs). In t...

The ablation material used during the National Ignition Campaign, a glowdischarge polymer (GDP), does not couple as efficiently as simulations indicated to the multipleshock inducing radiation drive environment created by laser power profile [1]. We investigate the performance of two other ablators, boron carbide (B4C) and high-density carbon (HDC) and compare with GDP under the same hohlraum c...

Limiting casting expression speed was obtained and the flow redistribution thermal history in a horizontal direct-chill (HDC) predicted using numerical modeling approach. The governing solidification equations were non-dimensionalized to understand relevant contribution of each term processes HDC system. effect an increase on characteristics sump length represented by Péclet number Pe. Details ...

A miniature, multifunctional hybrid organic directional coupler (HDC), constructed from two different flexible crystals, splits the optical signal and delivers input-dependent outputs.

Processing large amounts of data, especially in learning algorithms, poses a challenge for current embedded computing systems. Hyperdimensional (HD) (HDC) is brain-inspired paradigm that works with high-dimensional vectors called hypervectors . HDC replaces several complex computations bitwise and simpler arithmetic operations at the expense an increased amount data due to mapping into space. T...