نتایج جستجو برای: رزوناتور با مدچندگانه mmr

تعداد نتایج: 672710  

2013
Bharat Randive Vishal Diwan Ayesha De Costa

BACKGROUND India accounts for 19% of global maternal deaths, three-quarters of which come from nine states. In 2005, India launched a conditional cash transfer (CCT) programme, Janani Suraksha Yojana (JSY), to reduce maternal mortality ratio (MMR) through promotion of institutional births. JSY is the largest CCT in the world. In the nine states with relatively lower socioeconomic levels, JSY pr...

Journal: :The British journal of general practice : the journal of the Royal College of General Practitioners 2002
Mary E Ramsay J Yarwood D Lewis H Campbell J M White

BACKGROUND The measles, mumps and rubella (MMR) vaccine has been the focus of considerable adverse publicity in recent years. AIM To describe recent trends in parental attitudes to, and coverage of, MMR vaccine. DESIGN OF STUDY Routine surveillance of vaccine coverage and cross-sectional surveys of parental attitudes. SETTING All health authorities in England (vaccine coverage) and 132 en...

Journal: :BMJ 2002
Brent Taylor Elizabeth Miller Raghu Lingam Nick Andrews Andrea Simmons Julia Stowe

OBJECTIVES To investigate whether measles, mumps, and rubella (MMR) vaccination is associated with bowel problems and developmental regression in children with autism, looking for evidence of a "new variant" form of autism. DESIGN Population study with case note review linked to independently recorded vaccine data. SETTING Five health districts in north east London. PARTICIPANTS 278 child...

2017
Mohammed Tarique Moaz Ahmad Manish Chauhan Renu Tuteja

Malaria a major parasitic infection globally particularly in tropical and sub-tropical regions of the world is responsible for about 198 million cases and estimated deaths due to this disease are about 0.6 million. The emergence of drug resistance in the malaria parasite is alarming and it is necessary to understand its underlying cause and molecular mechanisms. It has been established that dru...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011
G Hutchins K Handley F L Baehner M Lopatin H Yaziji M Lee M T Seymour D J Kerr R G Gray P Quirke

403 Background: Colorectal cancer patients with deficient mismatch repair (dMMR) have significantly fewer recurrences and may respond less well to chemotherapy. Immunohistochemical (IHC) determination of MMR status is therefore recommended to identify patients in whom adjuvant therapy is not indicated, but little is known regarding the variability of assay results. We aimed to define MMR IHC as...

Journal: :Cancer prevention research 2012
Matthew B Yurgelun Ajay Goel Jason L Hornick Ananda Sen Danielle Kim Turgeon Mack T Ruffin Norman E Marcon John A Baron Robert S Bresalier Sapna Syngal Dean E Brenner C Richard Boland Elena M Stoffel

Colorectal cancers associated with Lynch syndrome are characterized by deficient DNA mismatch repair (MMR) function. Our aim was to evaluate the prevalence of microsatellite instability (MSI) and loss of MMR protein expression in Lynch syndrome-associated polyps. Sixty-two colorectal polyps--37 adenomatous polyps, 23 hyperplastic polyps, and 2 sessile serrated polyps (SSP)--from 34 subjects wit...

2014
Emmanuel Thompson Seidu Sofo

Sub-Saharan Africa has the highest ratio of maternal deaths in the world. Despite some progress, it is uncertain if Ghana (like other sub-Saharan countries) can reduce, by three-quarters, the maternal mortality ratio (MMR) by the year 2015 Therefore, the primary purpose of this study was to determine the predictors of MMR in Ghana. The study utilized data from the Demographic and Health Survey ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Antoni Castells Artemio Payá Cristina Alenda Francisco Rodríguez-Moranta Rubén Agrelo Montserrat Andreu Virgínia Piñol Sergi Castellví-Bel Rodrigo Jover Xavier Llor Elisenda Pons J Ignasi Elizalde Xavier Bessa Javier Alcedo Joan Saló Enrique Medina Antonio Naranjo Manel Esteller Josep M Piqué

BACKGROUND Cyclooxygenase 2 (COX-2) overexpression is a frequent but not universal event in colorectal cancer. It has been suggested that COX-2 protein expression is reduced in colorectal cancer with a defective mismatch repair (MMR) system, a phenomenon commonly associated with hereditary nonpolyposis colorectal cancer (HNPCC) but also present in up to 15% of sporadic tumors. AIM To assess C...

Journal: :Cell 2013
Christine K. Schmidt Stephen P. Jackson

Trimethylation of histone H3 on Lys36 (H3K36me3) by SETD2 is linked to actively transcribed regions. Li et al. identify a novel role for H3K36me3 that facilitates DNA mismatch repair (MMR) in cells by targeting the MMR machinery to chromatin during the cell cycle, thereby explaining certain cases of MMR-defective cancers.

Journal: :Archives of disease in childhood 2001
E Miller P Waight C P Farrington N Andrews J Stowe B Taylor

A CAUSAL ASSOCIATION BETWEEN MEASLES: mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vacci...

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