BACKGROUND Multimorbidity, the co-existence of two or more (2+) long-term conditions in an individual, is common among problem drug abusers. OBJECTIVE To delineate the patterns, multimorbidity prevalence, and disease severity in patients enrolled in a community-based primary care methadone maintenance treatment (MMT) programme. DESIGN This was a retrospective cohort study (n=274). The compa...

Background: Methadone maintenance therapy (MMT) was started as a pilot project in Malaysia in 2005, and many individuals have benefited from it. Aim: This study aimed to examine the retention rate among patients enrolled in a tertiary hospital MMT programme in Malaysia, as well as factors predicting retention and mortality among these patients. Methods: A total of 164 patients were enrolled in ...

We review drug abuse treatment as a means of preventing infection with HIV. Thirty-three studies, with an aggregate of over seventeen thousand subjects, were published in peer-reviewed journals from 1988-1998. Research on the utility of drug abuse treatment as an HIV prevention strategy has focused primarily on methadone maintenance treatment (MMT) rather than other modalities such as residenti...

BACKGROUND Compliance with methadone maintenance treatment (MMT) in China is poor. OBJECTIVE To evaluate the effects of adjunctive contingency management (CM) on the efficacy of methadone maintenance treatment (MMT) in patients with opioid dependence. HYPOTHESIS A 12-week prize-based contingency management (CM) intervention can increase the retention and compliance of heroin abusers to stan...

Vascular endothelial growth factor (VEGF) is up-regulated during mesothelial to mesenchymal transition (MMT) and has been associated with peritoneal membrane dysfunction in peritoneal dialysis (PD) patients. It has been shown that normal and malignant mesothelial cells (MCs) express VEGF receptors (VEGFRs) and co-receptors and that VEGF is an autocrine growth factor for mesothelioma. Hence, we ...

Three different protocols for the preparation of polymer layered silicate nanocomposites based upon a tri-functional epoxy resin, triglycidyl para-amino phenol (TGAP), have been compared in respect of the cure kinetics, the nanostructure and their mechanical properties. The three preparation procedures involve 2 wt% and 5 wt% of organically modified montmorillonite (MMT), and are: isothermal cu...

Preoperative risk assessment may fail in most patients who may be exposed to postoperative neurological sequelae. The aim of this study was to assess the effects of Fentanyl added to epidural levobupivacaine on cerebral oxygenation and cognitive functions. There was a negative correlation between age and MMT, and a positive correlation between SpO2 and MMT. MMT scores of Group 2 at postoperativ...

In this work, maghemite intercalated montmorillonite (γFe₂O₃-MMT)/polymer nanocomposites loaded with 1 or 2 wt.% of nanofillers were obtained by photopolymerization of difunctional acrylate monomers. The γFe₂O₃-MMT nanofillers were prepared by a new method based on the in situ formation of maghemite in the interlayer space of Fe-MMT using a three step process. X-ray diffraction (XRD), chemical ...

BACKGROUND The commencement of methadone maintenance therapy (MMT) in 2005 represents a quantum leap in the management of heroin dependence in Malaysia. OBJECTIVE To examine the 2-year outcomes of this modality in the treatment of heroin dependence with respect to the quality of life (QOL), heroin abstinence, and rate of employment among heroin dependants attending the Tengku Ampuan Afzan Hos...