The nucleus reticularis pontis oralis (RPO) and nucleus reticularis pontis caudalis (RPC) are implicated in the generation of rapid eye movement sleep (REM). Work in cats has indicated that GABA in RPO plays a role in the regulation of REM. We assessed REM after local microinjections into RPO and RPC of the gamma-aminobutyric acid-A (GABA(A)) agonist, muscimol (MUS), and the GABA(A) antagonist,...

Retinal progenitor cells (RPCs) hold great potential for the treatment of retinal degenerative diseases. However, their proliferation capacity and differentiation potential towards specific retinal neurons are limited, which limit their future clinical applications. Thus, it is important to improve the RPCs' ability to proliferate and differentiate. Currently, epidermal growth factor (EGF) is c...

BACKGROUND The first-line treatment for resectable pancreatic cancer (RPC) is surgical resection. However, our patients have often experienced early recurrence after curative resection for RPC, with desperately poor prognosis. Some reports indicated that minimally distant metastasis not detected at operation might cause early recurrence. The present study aimed to identify preoperative clinicop...

The study of rockburst criterion is the key to predict occurrence rockburst. Based on energy principle, a new multi-parameter (RPC) were established. accuracy and applicability some typical engineering examples in China verified by using classical criteria newly proposed RPC. research results show that: RPC comprehensively considers various stress states surrounding rock mass unit, reflects int...

In the field of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast cancer, current research efforts in computer-aided diagnosis (CADx) are mainly focused on the temporal series of T1-weighted images acquired during uptake of a contrast agent, processing morphological and kinetic information. Although static T2weighted images are usually part of DCE-MRI protocols, they are ...

GEANT4 is a toolkit for simulating the passage of particles though matter, which contains a complete range of functionality including tracking, geometry, physics models, and hits. In this article, an attempt to use GEANT4 Monte Carlo code to watch a double-gap Resistive Plate Chamber's (RPC) response to neutrons is presented. The simulation calculations of the double-gap RPC have been evaluated...