Anaplastic large cell lymphoma (ALCL) is a histological subtype of non-Hodgkin lymphoma, largely characterized by anaplastic kinase (ALK) positivity, resulting from the chromosomal translocation t(2;5). We report pediatric case ALK-positive ALCL with primary concomitant involvement bone and central nervous system (CNS); thereafter, literature review about CNS was conducted. According to analyze...

Background The central nervous system international prognostic index (CNS-IPI) is being used widely for the identification of patients with diffuse large B cell lymphoma (DLBCL) a high risk (CNS) relapse. aim our study to confirm value CNS-IPI in predicting CNS relapse young population and evaluate its impact on selection prophylaxis. Methods We retrospectively reviewed diagnosed DLBCL who were...

Guillain-Barré syndrome (GBS) and its variants are parainfectious (2/3 cases) neurological illness involving the lower motor neuron but they can also involve central nervous system (CNS). Bickerstaff brainstem encephalitis (BBE) Miller Fisher (MFS) two of GBS with CNS involvement. The present case series highlights variable presentation laboratory findings in BBE MFS, which may help clinicians ...