background: age-related differences in the ethoxyresorufin o-deethylase (erod) activity of cyp1a1 and its inducibility in rats may determine the toxic potential of acetaminophen.  this study was carried out to compare the effects of acetaminophen (apap) and β-naphthoflavone (βnf) on cyp1a1 activity in young and adult rats. methods: for this purpose, young and adult rats (n = four / group) were...

BACKGROUND AND AIM: This study was designed to assess the correlation between chronological age and modified Demirjian estimated dental age.METHODS: Panoramic radiographs of 183 Patients between 13.5 and 20.5 years old were assessed for the developmental stage of lower right third molars. Student’s t-test was used to measure the same hypothesis of the chronological age and estimated modified De...

Background: The variability in the developmental skills is reduced after the first three years of life; therefore, it is necessary to identify and manage early developmental delays. Aim: The aim of this study was to investigate the effect of developmental stimulation program on the developmental measures of the toddlers. Method: The present randomized controlled clinical trial was conducted on ...

Background & Aims: Accurate knowledge about gestational age is very important in taking decision for pregnancy management and termination. According to Naegele’s rule the length of pregnancy is 280 days after LMP and according to studies performed in Harvard University, duration of pregnancy in nullipare and multipare women has been respectively 288 and 283 days and according to a study perform...

Background: Congenital malformation (CM) is the major health problems in childhood because treatment and rehabilitation of children with CM is costly and complete recovery is usually impossible. For most of single primary defect the etiology is unknown. The aim of this study was to determine frequency of CM and its association with maternal age. Materials and Methods: This descriptive-observati...