Denis Malvy ([email protected]) Khaled Ezzedine ([email protected]) Maria Mamani-Matsuda ([email protected]) Brigitte Autran ([email protected]) Hughes Tolou ([email protected]) Marie-Catherine Receveur ([email protected]) Thierry Pistone ([email protected]) Jérôme Rambert (jerome.rambert@u-bordeaux2...

We describe an integrated approach for detection of diagnostic markers using in situ assembled optical diffraction gratings in combination with immunomagnetic capture. Folate receptor (FR), a serum protein indicative of various cancers, was chosen as a model system to demonstrate the potential of the method. Magnetic beads coupled to FR antibody were used to capture FR from serum. The FR-bound ...

A suitable measure for the similarity of shapes represented by parameterized curves or surfaces is the Fr echet distance. Whereas e cient algorithms are known for computing the Fr echet distance of polygonal curves, the same problem for triangulated surfaces is NP-hard. Furthermore, it remained open whether it is computable at all. Using a discrete approximation we show that it is upper semi-co...

RATIONALE AND OBJECTIVE Receptor-targeted delivery of imaging and therapeutic agents can lead to enhanced efficacy for both. Multimodality imaging offers unique advantages over traditional single modality imaging. Tumor marker folate receptor (FR)-targeted fluorescent paramagnetic bimodal liposomes were synthesized to co-deliver paramagnetic and fluorescence agents for magnetic resonance (MR) a...

one of the important issues in hydraulic engineering is inspection of local scour depth around bridge pier. using piles is one of the ways for confronting local scour and erosion. in this study, the experiments were conducted in an 8m long, 0.5m deep and 0.25m wide flume. and the effectof using piles and number of them observed on the amount of scour in three different frude numbers. the shape ...

The degree of nutrient enhancement during the newborn period may modulate programming of appetite-regulating hormones, body composition, and propensity to adult obesity in intrauterine growth-restricted (IUGR) newborns. Pregnant rats received, from day 10 to term gestation and throughout lactation, ad libitum food (AdLib) or 50% food restriction (FR) to produce IUGR newborns. AdLib vs. FR offsp...

Dynamic balance ability related to maintaining postural stability during movement is closely tied to fall risk in the elderly. The functional reach (FR) test has been developed to evaluate their dynamic balance. Although a simple and new FR test using an elastic stick has been proposed by modifying the above original FR test, the abilities related to both FR tests are judged to differ because o...