background and objective: parkinson's disease (pd) is a movement disorder with debilitating symptoms. available treatments for pd mainly include its symptomatic relief with no prevention of its progression. due to the iron-chelating and antioxidant effect of phytic acid (pa), this study was conducted to assess its protective effect in 6-hydroxydopamine-induced model of pd in rat. materials and ...

chiral pyrrolidines and pyrrolizidines with spirooxindole ring systems are the central skeletons for numerous alkaloids and pharmacologically important compounds. gelesmine, pseudotabersonine, formosanine, isoformosanine, morroniside and mitraphylline are some of the alkaloids containing spirooxindole ring systems. derivatives of spirooxindole find very wide biological applications as anti micr...

background: in order to diagnose the site of thrombi, radiolabeled streptokinase can be prepared. the radiolabeled compound can be used in imaging of thrombi in many cardiovascular diseases. materials and methods: streptokinase was successively labeled with [67ga]-gallium chloride using cyclic dtpa-dianhydride. the conjugation with dtpa was optimized for concentration, time and temperature foll...

1920x1200 abstract: background: down syndrome is the most common chromosomal abnormality due to 21 trisomy that usually is accompany with congenital heart diseases. about fifty present of children with down syndrome have heart defects. this study was designed for the aim of abundance percents of septal heart defects in children with down syndrome at imam reza and imam ali hospitals in kermansha...

bachground: endometriosis is a disease of female genital system, which is defined by the presence of ectopic endometrial tissue outside the uterine cavity. il-8 is an autocrine growth factor in the endometrium that contributes to the pathogenesis of endometriosis. the aim of this study was to investigate the association between -251t/a polymorphism in the il-8 gene and endometriosis risk in ira...

background: p e r io d ontal d i s e ase i s a c h ro ni c des t ructi v e d i s e a s e w h ich o ccurs in adults, young people, and children .   perio d ontal disease and periodontal pathoge n s ha v e been associ a ted with se v er a l syste m ic dise a ses and more recen t ly, se v e r a l stu d ies have sug g es te d the relat i o n ship bet w een p e rio d ontal d isease and cancer. stu d...

urinary 1-hydroxypyrene is frequently used as a major metabolite and biological indicator of the overall exposure to polycyclic aromatic hydrocarbons. in this study, solid phase extraction was appropriately conditioned with regard to sample ph, sample concentration, loading flow rate, elution solvent, washing solvent, sample volume and sorbent mass. octadecyl silica cartridge (c18) was used as ...

the aim of this study was to evaluate the concentrations of reproductive hormones in blood plasma and in follicular fluids of different sized follicles during various stages of the estrous cycle in holstein cattle. jugular blood samples from 42 adult holstein cattle were collected immediately after the slaughter. antral fluids from small (4-5 mm), medium (6-9 mm) and large (10-20 mm) follicles ...