postcapillary venules. With continuous high perfusion, the capillary bed disappears with loss of its resistive function to form a high-pressure arterio-venous communication. In calcinosis, Raynaud’s disease, sclerodactyly, telangiectasia syndrome (CRST), studies demonstrate that the telangiectases (telangiectatic mats) are composed only of vasodilated post-capillary venules without infl ammator...

We report the case of a young woman with hereditary hemorrhagic telangiectasia (HHT) with severe liver involvement and pulmonary shunting. The medical imaging in this patient illustrates the severe shunting that can occur in these patients who often are asymptomatic. By showing this case, we want to highlight the role of liver transplantation in HHT with hepatic involvement.

In case of a cerebral abscess without known cause, Pulmonary arteriovenous malformations (PAVM) screening should be performed. If PAVM(s) is identified, Hereditary hemorrhagic telangiectasia (HHT) is very likely and should always be considered. This case shows the benefit of familial screening for HHT and PAVM.

This paper presents a vibration control method for the suppression of robotic arm. To understand causes in six-axis manipulator and then eliminate through an effective method, structure can be divided into two parts. First, variational mode decomposition (VMD) Hilbert–Huang transform (HHT) algorithm are integrated to analyze signal extract characteristics. Second, smooth trajectory planning is ...

BACKGROUND The anti-leukemic mechanism of homoharringtonine (HHT) differs from that of IM, and HHT is one of the most useful agents for use in patients with IM resistance or intolerance. The Bcl-6/p53 pathway has been shown to regulate the sensitivity of tumor cells to antitumor drugs. We tested whether HHT blocked the Bcl-6/p53 pathway in order to promote the apoptosis of IM-resistant cells in...

BACKGROUND Mutations in the endoglin (ENG) or ALK1 genes are responsible for hereditary hemorrhagic telangiectasia types 1 and 2 (HHT1 and HHT2), respectively, a dominant vascular dysplasia caused by haploinsufficiency. No formal mutation studies of patients with HHT have been conducted in Spain. METHODS ENG and ALK1 mutation analyses were carried out in 13 Spanish HHT patients diagnosed acco...

Hereditary hemorrhagic telangiectasia (HHT) is an inherited vascular dysplasia characterized by mucocutaneous telangiectasia and visceral arteriovenous malformations. Hepatic involvement with vascular malformations may lead to portal hypertension, biliary ischemia, and high-output cardiac failure. There is no curative treatment for the disease. Liver transplantation is indicated for life-threat...

H ereditary haemorrhagic telangiectasia (HHT or RenduOsler-Weber syndrome; MIM 187300) is characterised by vascular dysplasia and is inherited in an autosomal dominant manner. HHT occurs among many ethnic groups over a wide geographical area. Recent epidemiological studies have revealed an incidence for this disease of 1 in 5000– 8000. 2 In most cases, the manifestations of HHT are not present ...

BACKGROUND Heterotopic heart transplantation (HHT) in rodent animal models represents an important technique enabling studies on organ transplantation immunology and pharmaceutical development. Recent investigations used nonworking HHT designs, with the left ventricle (LV) bypassed in the anastomosis system. In spite of their principal success, the lack of orthogonal ventricular filling leads t...

The Hilbert-Huang transform (HHT) is a novel, adaptive approach to time series analysis. It does not impose a basis set on the data or otherwise make assumptions about the data form, and so the time–frequency decomposition is not limited by spreading due to uncertainty. Because of the high resolution of the time–frequency, we investigate the possibility of the application of the HHT to the sear...