Abstract Study question Is it possible to predict clinical pregnancy using Machine Learning models on day 6 after embryo transfer an acceptable degree of certainty? Summary answer Using selected biochemical markers is build a machine learning model pregnancy. What known already Human chorionic gonadotropin (β-hCG) considered the main early predictor Due fact that highest percentage spontaneous ...

OBJECTIVE To report an extremely rare case of spontaneous uterine perforation of choriocarcinoma with negative beta-human chorionic gonadotropin (β-hCG) post-chemotherapy. CLINICAL PRESENTATION AND INTERVENTION We present a 35-year-old choriocarcinoma patient whose serial serum β-hCG levels following a fifth course of chemotherapy had been within the normal range, but who developed spontaneou...

Nowadays, the prevalence of Multiple Myeloma (MM) seems to have been increasing among young females. Here, we report that thalidomide is contraindicated in pregnant women diagnosed with MM and those desirous of subsequent pregnancy. In this case report, we compared the clinical response of Thalidomide-Dexamethasone therapy in a post-abortive woman with persistently elevated β-hCG levels due to ...

Background: Patients with ectopic pregnancy and low serum β-HCG concentrations are commonly treated systemic methotrexate. Aim: To compare the outcome of methotrexate versus expectant management for females presenting pregnancy. Study design: Randomized controlled trial. Methodology: Females (n=140) were enrolled in study. Blood sample was taken beta-HCG noted. Then randomly divided two groups ...

Objectives: To study the role of β – hCG in pathogenesis of preeclampsia and its association with severity of preeclampsia. Materials and Methods: The prospective randomized study was conducted on 500 pregnant women of gestational pregnancy between 12 24 weeks with singleton pregnancy. According to American college of obstetrics and gynecology [ACOG, 2013], patients were classified into three g...

Objective(s): Amyloid β plaques, in Alzheimer’s disease, are deposits in different areas of the brain such as prefrontal cortex, molecular layer of the cerebellum, and the hippocampal formation. Amyloid β aggregates lead to the release of cytochrome c and finally neuronal cell death in brain tissue. hCG has critical roles in brain development, neuron differentiation, and function. Therefore, we...

Background: Pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin (free β-hCG) as valuable biochemical biomarkers are used to screen down syndrome, Edwards syndrome, and Patau syndrome in the first trimester of pregnancy. Closed immunoassay analyzers are regarded as sophisticated platforms to measure biochemical biomarkers. This study compared the performance of...

Amaç: Plasenta previa (PP) tanılı olgularda plasenta akreta indeks (PAI) skoru ile ilk trimester serum belirteçlerinin (PAPP-A, serbest β HCG) Akreta Spektrumu (PAS) öngörüsündeki yerini araştırmayı amaçladık.
 Gereç ve Yöntemler: Çalışmamıza 30 PAS, adezyon anomalisi saptanmayan olgusu 60 sağlıklı gebe dahil edildi. Çalışmaya edilen olguların, üçüncü trimesterda PAI belirlendi, ardından b...

Objective: To determine medians of pregnancy-associated plasma protein-A (PAPP-A) and free β subunit Human Chorionic Gonadotropin (hCG-β) in the first trimester healthy pregnant women visiting tertiary care hospital.
 Study Design: Cross-sectional study.
 Place Duration Study: Department Chemical Pathology Endocrinology, Armed Forces Institute (AFIP) from May 2018 to 2019.
 Metho...