The Eph family of receptor tyrosine kinases and their ephrin ligands are mediators of cell-cell communication. Cleavage of ephrin-A2 by the ADAM10 membrane metalloprotease enables contact repulsion between Eph- and ephrin-expressing cells. How ADAM10 interacts with ephrins in a regulated manner to cleave only Eph bound ephrin molecules remains unclear. The structure of ADAM10 disintegrin and cy...

Stream ciphers play an important role in those applications where high throughput remains critical and resources are very restricted e.g. in Europe and North America, A5/1 is widely used stream cipher that ensure confidentiality of conversations in GSM mobile phones. However careful security analysis of such cipher is very important due to widespread practical applicability. The basic building ...

Annexin A5 (annexin V, anchorin CII) represents the prototype member of the large annexin family, characterized by its ability to interact with phospholipids in a calcium-dependent manner and to form calcium-specific ion channels. Despite intense biochemical analysis, the in vivo expression and function of this annexin during mouse development, still remains unclear. Immunohistochemistry, in si...

Using cloned DNA complementary to mouse dihydrofolate reductase (DHFR) mRNA, the organization of the hamster DHFR gene has been determined in two baby hamster kidney (BHK) cell lines, A5 and B1. A5 cells are highly methotrexate-resistant, containing 200-fold more copies of the DHFR gene than do the parental B1 cells. The DHFR gene has the same organization in A5 and B1 cells, suggesting that it...

Selecting and utilizing proper virtual machines in a virtualized cloud platform to achieve high availability, throughput, reliability, as well as low cost and makespan is very important. The importance lies in the adaptive resource provisioning to satisfy variant of workloads. An Adaptive Accessing Aware Algorithm (A5) is proposed in this paper to deal with this conflicting objective optimizati...

Eph receptors and ephrin ligands are large families of cell surface proteins which have established roles in axonal growth and guidance. These are well characterized in the visual and somatosensory systems but are less well documented in the auditory pathway. We examined the possible functional role of two ephrin genes (ephrin-A2 and ephrin-A5) in the auditory system by measuring auditory brain...

Stroke causes loss of neurological function. Recovery after stroke is facilitated by forced use of the affected limb and is associated with sprouting of new connections, a process that is sharply confined in the adult brain. We show that ephrin-A5 is induced in reactive astrocytes in periinfarct cortex and is an inhibitor of axonal sprouting and motor recovery in stroke. Blockade of ephrin-A5 s...

Global System for Mobile Communications (GSM) is one of the most commonly used cellular technologies in the world. One of the objectives in mobile communication systems is the security of the exchanged data. GSM employs many cryptographic algorithms for security like A5/1, A5/2 and A5/3. Even so, these algorithms do not provide sufficient level of security for protecting the confidentiality of ...

In this paper, the hardware implementations of five representative stream ciphers are compared in terms of performance and consumed area in an FPGA device. The ciphers used for the comparison are the A5/1, W7, E0, RC4 and Helix. The first three ones have been used for the security part of well-known standards, especially wireless communication protocols. The Helix cipher is a recently introduce...