The aim of this study was to assess the effects of chronic combined exposure to low, environmental doses of Cd, Pb, and Mn on oxidative stress in the liver and heart of rats and on their liver function parameters. Male Wistar rats were divided randomly into eight groups. For nine months controls were receiving drinking water alone, whereas the exposed groups were receiving drinking water with P...

the concentration of cu, mn, ni and zn were determined in tomatoes and onions samples using atomic absorption spectrometry. a total of 32 samples each of tomatoes and onions were collected from the exposed and control sites for analysis. the trace metals (cu, mn, ni and zn) concentration in tomatoes wee found to be 6.2406, 6.5521 , 5.7375 and 8.9297 mg/kg-1, respectively. while those of onions ...

Both the adenylylated and unadenylylated forms of Escherichia coli glutamine synthetase catalyze the formation of pyrrolidone carboxylate from glutamate in the presence of ATP and divalent metal ions (Mg++ or Mn++) and in the absence of ammonia. The unadenylylated enzyme catalyzes this reaction more rapidly with Mg++ than with Mn++, while the adenylylated enzyme catalyzes it more rapidly with M...

BACKGROUND The aim of the study was to evaluate the toxicokinetics of 2-methylnaphtalene (2-MN) during and after inhalation exposure. MATERIAL AND METHODS Male Wistar rats were exposed to 2-MN vapours at nominal concentrations of 200 or 400 mg/m3 in the dynamic inhalation chamber for 6 hours or 5 days (6 h/day). Blood samples were collected during and after exposure. Blood concentrations of 2...

BACKGROUND Manganese (Mn) is widely used in industries including the manufacture of Mn-iron (Fe) alloy. Occupational Mn overexposure causes manganism. Mn is known to affect Fe metabolism; this study was designed to test the hypothesis that workers exposed to Mn may have an altered expression of mRNAs encoding proteins in Fe metabolism. METHODS Workers occupationally exposed to Mn (n = 71) fro...