نتایج جستجو برای: β agonist
تعداد نتایج: 224525 فیلتر نتایج به سال:
BACKGROUND AND PURPOSE GPR35 is a poorly characterized G protein-coupled receptor at which kynurenic acid has been suggested to be the endogenous ligand. We wished to test this and develop assays appropriate for the study of this receptor. EXPERIMENTAL APPROACH Human and rat orthologues of GPR35 were engineered and expressed and assays developed to assess interaction with β-arrestin-2, activa...
GPR120 is a long-chain fatty acid receptor that stimulates incretin hormone release from colonic endocrine cells and is implicated in macrophage and adipocyte function. The functional consequences of long (L) and short (S) human GPR120 splice variants, which differ by insertion of 16 amino acids in the third intracellular loop, are currently unknown. Here we compare signaling and intracellular ...
Bronchodilator tolerance and rebound bronchoconstriction during regular inhaled β -agonist treatment
در سال¬های اخیر، نگرانی¬های فزاینده¬ی زیست محیطی سبب شده است تا توجه به اکوتوریسم به عنوان نوعی از گردشگری پایدار فزونی یابد. طرح¬های حفاظتی راهی برای توسعه¬ی اکوتوریسم در بسیاری از جوامع در حال توسعه برای رسیدن به پایداری در حال پیگیری است. این طرح¬ها می¬توانند شامل برنامه¬هایی برای توانمندکردن جامعه¬ی محلی به خصوص زنان باشند، چرا که اکوتوریسم پتانسیل زیادی برای توانمندکردن و ایجاد رفاه برای ج...
Objective: Asthma is an increasing chronic respiratory disease affecting over 300 million people worldwide. Several studies have shown that herbal remedies may improve asthma control and reduce asthma symptoms. In this study, the effects of short-course administration of an herbal mixture (ASMATUSTM) in asthmatic children during viral respiratory tract infection, were evaluated. Materials and M...
BACKGROUND In un-resuscitated rodent models of septic shock, the peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) agonist GW0742 improved visceral organ function. Therefore, we tested the hypothesis whether GW0742 would attenuate kidney injury during long-term, resuscitated, porcine polymicrobial septic shock. METHODS Six, 12, and 18 h after the induction of fecal peritonitis by inoc...
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