Endosulfan, a chlorinated cyclodiene insecticide, was administered orally at 1.5, 3, 6, and 9 mg/kg per day to normal hemicastrated virgin mice for 15 consecutive days to examine the effect on ovarian function. Sham-operated and hemicastrated control mice were administered a similar volume of olive oil. The vaginal smear and body weight of the mice were recorded daily and mice were sacrificed o...

Pesticide degradation is the challenges of the day were safe, rapid and economically efficient methods are searched. In the process present paper made an attempt to isolate secondary metabolites from Cipadessa baccifera and degrade endosulfan at two different concentrations. Significant degradation was obtained with secondary metabolites with P value = <0.0001 for both 1000 and 2000 μg/ml conce...

Endosulfan exposure (8 and 16 mg/kg) to rats significantly decreased the activities of superoxide dismutase and catalase, level of reduced glutathione and increased lipid peroxidation. The primary and secondary antiSRBC antibody titers, plaque forming cells counts and delayed hypersensivity reaction, and the TH1 or TH2 cytokines levels were significantly suppressed in a dose dependent manner. L...

OBJECTIVES Pancreas pathology in subacute endosulfan toxicity and the effect of vitamin C in rabbits were studied. METHODS : Twenty-four rabbits in 4 groups were used. The rabbits in group END were given a daily sublethal dose (1 mg/kg of body weight) of endosulfan in corn oil by oral gavage for 6 weeks. Group END+C received the same dose of endosulfan and also vitamin C (20 mg/kg) every othe...

The effect of soil properties like adsorption, desorption, movement and distribution of endosulfan (1, 2, 3, 4, 7, 7-hexachlorobicyclo (2, 2, 1)-2-heptene-5, 6-bisoxymethlene sulfite) in two tropical soils, sandy loam and sandy clay soil from Mysore, Karnataka state were studied respectively. The results indicated that soils with different physico-chemical properties have different effects on t...

AIM The present study was undertaken to estimate the current status of residues of organochlorine pesticides (OCPs), organophosphates (OPs) and synthetic pyrethroids (SPs) pesticides in human blood. MATERIALS AND METHODS Human blood samples were analyzed by gas chromatography and confirmed by gas chromatography-mass spectrometry in selective ion monitoring mode. RESULTS The gas chromatograp...