OBJECTIVES To assess knowledge, pregnancy attitudes and contraceptive practices in relation to the Zika virus outbreak in Brazil. METHODS We interviewed 526 women 18 to 49 years old in primary health services in a Northeastern capital of Brazil, in 2016. They provided information about their knowledge of Zika transmission and health consequences, their receipt of counseling related to sexual ...

Approximately 70 years ago, new flavivirus was discovered in the Zika forest of Uganda (Dick et al., 1952). The eponymous virus is an arthropod-borne human pathogen that caused infrequent infections with relatively mild illness in Africa and received relatively little attention until recently. Over the last several years the virus has spread into Southeast Asia, across the Pacific and, in 2015,...

Zika virus infection during pregnancy remains a serious health threat in Puerto Rico. Infection during pregnancy can cause microcephaly, brain abnormalities, and other severe birth defects (1). From January 1, 2016 through March 29, 2017, Puerto Rico reported approximately 3,300 pregnant women with laboratory evidence of possible Zika virus infection (2). There is currently no vaccine or interv...

Following of the emergence of Zika virus in Brazil in 2015, an epidemiological surveillance system was quickly implemented in the French overseas Territories of America (FTA) according to previous experience with dengue and chikungunya and has detected first cases of Zika. General practitioners and medical microbiologists were invited to report all clinically suspected cases of Zika, laboratory...

Further investigation of the role of each type of these cytokines during Zika virus infection is urgently needed. The dendritic cell (DC) is one of the main target cells during infection by various flaviviruses, for examples, DENV, WNV and presumably the most potent antigen-presenting cell (APC)s. Blood DCs of convalescent Zika-virus infection patients demonstrated similarly effective antigen c...

Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas...

The recent article on ‘‘Hearing loss in congenital Zika virus’’ is very interesting.1 Leal et al. reported an interesting case of sensorineural hearing loss in a case of congenital Zika virus.1 In fact, it is no doubt that Zika virus can induce teratogenic effect and the main pathology is on the fetal neurological system. However, the myth is the exact mechanism underlying the hearing loss in t...

The spread of Zika virus in the Americas has been associated with a surge in Guillain-Barré syndrome (GBS) cases. Given the severity of GBS, territories affected by Zika virus need to plan health-care resources to manage GBS patients. To inform such planning in Martinique, we analyzed Zika virus surveillance and GBS data from Martinique in real time with a modeling framework that captured dynam...

Before 2007, no Zika virus outbreak had been recorded, and Zika virus was deemed to cause mild infections. In 2013–14, an outbreak occurred in French Polynesia associated with an increased rate of Guillain-Barré syndrome following Zika infections. Zika virus spread in the Pacifi c region in 2014 and then, in 2015, to Brazil where an association between Zika infection and microcephaly is under i...

INTRODUCTION Zika virus has been documented since 1952, but been associated with mild, self-limiting disease. Zika virus is classified as an arbovirus from a family of Flaviviridae and primarily spread by Aedes Aegypti mosquitos. However, in a large outbreak in Brazil in 2015, Zika virus has been associated with microcephaly. METHODS In this review we applied the Bradford-Hill viewpoints  to ...