Analysis of the short-term dynamics of human immunodeficiency virus (HIV) type 1 infection in response to drug therapy has elucidated crucial kinetic properties of viral dynamics in vivo (D. D. Ho et al., Nature 373:123-126, 1995; A. S. Perelson et al., Science 271:1582-1586, 1996; X. Wei et al., Nature 373:117-122, 1995). Here we investigated long-term changes in virus load in patients treated...

Apple hammerhead viroid (AHVd) was detected in the apple cultivar ‘Šampion’ and mixed infection with Solanum nigrum ilarvirus 1 (SnIV-1) cultivars ‘Selena’ ‘Jonagored Supra’, using a high-throughput sequencing method. Experiments were conducted to eliminate both pathogens apples meristem tip cultures combination antivirotics ribavirin, rimantadine, zidovudine. Elimination of verified by repeate...

Background Hematological complications such as Zidovudine(ZDV) associated anemia are among the commonly reported adverse drug reactions of Antiretroviral Therapy(ART). Little is known about ZDV associated anemia in developing countries like Ethiopia. Methods Comparative retrospective cohort study was conducted at the ART Clinic of St. Paul Hospital Millennium Medical College from February 201...