نتایج جستجو برای: yolk sac tumor
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Most primary intracranial germ-cell tumors are germinomas and teratomas. Less frequent are embryonal carcinomas, choriocarcinomas, and yolk-sac (endodermal sinus) tumors in various admixtures and degrees of purity. Teilum [1] first used the term endodermal sinus tumor in 1959 to describe those tumors (whether ovarian, testicular, or extragonadal) that originate in primitive germ cells of extrae...
Testicular germ cell tumors (TGCTs) represent the most common type of solid tumors among men aged 15 to 40 years. An increasing incidence has been recorded in developed countries. In clinical practice, TGCTs are classified as seminomas and non-seminomatous tumors. Non-seminomatous tumors often contain multiple different cell types and can be further sub-divided according to the histological and...
BACKGROUND Intratumoral heterogeneity presents a major obstacle to the widespread implementation of precision medicine. The authors assessed the origin of intratumoral heterogeneity in nonseminomatous germ cell tumor of the testis (NSGCT) and identified distinct tumor subtypes and a potentially lethal phenotype. METHODS In this retrospective study, all consecutive patients who had been diagno...
AIMS To investigate a potential diagnostic use of alpha fetoprotein (alpha FP) isoform analysis by lectin affinity electrophoresis to distinguish between endodermal sinus tumours arising in the vagina in infants from those at other sites. METHODS alpha FP in the serum of a patient with a vaginal endodermal sinus tumour was analysed for its isoforms by lectin affinity electrophoresis. The isof...
Germ cell tumors are rare neoplasms that mostly occur in the gonads, although they can also affect other body sites, especially the anterior mediastinum (50 to 70% of all extragonadal germ cell tumors). We report a case of a primary mediastinal yolk sac tumor, a rare and aggressive germ cell tumors subtype. This was a 38-year-old man who was admitted to Hospital do Servidor Público Estadual "Fr...
Sacrococcygeal teratoma (SCT) is the most common congenital tumor in neonates. SCT may be benign (mature and immature) or malignant. Malignancy is rare in SCT diagnosed before 2 months of age. Here, we describe a neonate having a mature teratoma with a focus of malignant yolk sac tumor within and the difficulties faced in its management.
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