نتایج جستجو برای: yac

تعداد نتایج: 835  

Journal: :DNA research : an international journal for rapid publication of reports on genes and genomes 1998
S Sato H Kotani R Hayashi Y G Liu D Shibata S Tabata

We have constructed a physical map of Arabidopsis thaliana chromosome 3 by ordering the clones from CIC YAC, P1, TAC and BAC libraries using the sequences of a variety of genetic and EST markers and terminal sequences of clones. The markers used were 112 DNA markers, 145 YAC end sequences, and 156 end sequences of P1, TAC and BAC clones. The entire genome of chromosome 3, except for the centrom...

Journal: :Nucleic acids research 1996
C N Chen Y Su P Baybayan A Siruno R Nagaraja R Mazzarella D Schlessinger E Chen

Ordered shotgun sequencing (OSS) has been successfully carried out with an Xq25 YAC substrate. yWXD703 DNA was subcloned into lambda phage and sequences of insert ends of the lambda subclones were used to generate a map to select a minimum tiling path of clones to be completely sequenced. The sequence of 135 038 nt contains the entire ANT2 cDNA as well as four other candidates suggested by comp...

Journal: :Human molecular genetics 1996
C Huxley E Passage A Manson G Putzu D Figarella-Branger J F Pellissier M Fontés

Construction of animal models of human inherited diseases is particularly important for testing gene therapy approaches. Towards this end, we constructed a mouse model for Charcot-Marie-Tooth disease type 1A by pronuclear injection of a YAC containing the human PMP22 gene. In one transgenic line, the YAC DNA is integrated in about eight copies and the PMP22 gene is strongly expressed to give a ...

Journal: :The Journal of Experimental Medicine 1983
H Binz M Fenner D Frei H Wigzell

Dimethylbenzanthracene-induced P1 sarcoma cells induce P1-specific antibodies in syngeneic DA rats. Antiidiotypic antibodies of specificity DA anti-(DA anti-P1) were induced against the tumor-specific antibodies and used to restimulate P1-primed DA T cells in vitro. Using antiidiotypic antibodies and T cell growth factor, P1-specific cytotoxic DA T cell clones were established by limiting dilut...

1999
Takashi Yokomori

This paper proposes a new model for DNA computation called YAC that is based on self-assembly principle. The advantages of the proposed model may be summarized as follows : (i) the model has the universal computability of Turing machines, (ii) nevertheless, it only requires surprisingly simple and basic biomolecular operations, i.e., besides annealing and melting in one-pot reaction, its comput...

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