نتایج جستجو برای: xenodiagnosis
تعداد نتایج: 156 فیلتر نتایج به سال:
Herein, we evaluated the treatment strategy employing a therapeutic heterologous vaccine composed of antigens of Leishmania braziliensis associated with MPL adjuvant (LBMPL vaccine) for visceral leishmaniasis (VL) in symptomatic dogs naturally infected by Leishmania infantum. Sixteen dogs received immunotherapy with MPL adjuvant (n = 6) or with a vaccine composed of antigens of L. braziliensis ...
Chagas disease has rightfully earned the designation as ‘‘the most neglected of the neglected diseases’’ [1]. Most of the 10–20 million people already infected with Trypanosoma cruzi, the protozoal agent of Chagas disease, are untreated, despite the existence of effective therapies. Diagnostics are largely archaic (xenodiagnosis—using the blood-feeding insect vectors to detect infection—is stil...
Chagas disease (American trypanosomiasis) is a major cause of morbidity and death in Latin America. An estimated 16-18 million persons are infected with the causative protozoan parasite, Trypanosoma cruzi, and 45,000 individuals are thought to die of the illness each year [1] . Accurate diagnosis of Chagas disease is necessary to permit appropriate treatment and monitoring, as well as for donor...
Chagas ́disease (CD) is caused by the protozoan parasite Trypanosoma cruzi, and was discovered in 1909 by the Brazilian physician Chagas [1]. T. cruzi is transmitted when the infected feces of the triatomino vector are inoculated through a bite site or through an intact mucous membrane of the mammalian host. Vector transmission is the classical form of CD acquisition. This transmission route has...
37 Chagas disease caused by Trypanosoma cruzi is endemic in Latin America .T cruzi 38 presents heterogeneous populations and comprises two main genetic lineages, named T. 39 cruzi I and T. cruzi II. The diagnosis in the chronic phase is based on conventional 40 serological tests including IIF and ELISA, and in the acute phase based on parasitological 41 methods, including hemoculture. The objec...
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