Background: Wartime missile injuries are frequently high-energy wounds that devitalize and contaminate tissue, with high risk for infection and wound complications. Debridement, irrigation, and closure by secondary intention are fundamental principles for the management of these injuries. However, closure by secondary intention was impractical in Iraqi patients. Therefore, wounds were closed de...

Wound washing with antiseptic liquid is one step in the management of chronic wounds. In infected wounds, expected to reduce bacterial colonies and help eradicate infection. One important pathogenic bacteria Acinetobacter Baumannii. These opportunistic germs can form colonies, especially patients receiving broad-spectrum antibiotic therapy, treatment ICU, on skin affected by burns. Antiseptic c...

Integrins have been shown to play important roles in embryonic development, wound healing, metastasis, and other biological processes. alphavbeta5 is a receptor for RGD-containing extracellular matrix proteins that has been suggested to be important in cutaneous wound healing and adenovirus infection. To examine the in vivo function of this receptor, we have generated mice lacking beta5 express...

Sepsis remains the major cause of death in patients with major burn injuries. In the present investigation we evaluated the interaction between burn injuries of varying severity and preexisting distant infection. We used Gram-negative bacteria (Pseudomonas aeruginosa and Proteus mirabilis) that were genetically engineered to be bioluminescent, which allowed for noninvasive, sequential optical i...

Abstract Neofusicoccum parvum is a recently reported pathogen affecting Theobroma cacao L., and has been isolated from symptomatic pods on Oahu Hawaii Islands. Determining infection routes virulence are essential for assessing the impact of N. production developing effective disease management strategies. Infection were determined by inoculating unwounded stems with six isolates alongside Lasio...

Chronic Venous Leg Ulcers (CVLUs) are vascular diseases and require complex wound care from a patient, wound, health personnel dressing factors. Cadexomer Iodine (CI) Polyhexamethylene Biguanide (PHMB) antimicrobial broad-spectrum washing fluids. The uncontrolled infection will complicate healing due to bacteria or plankton the biofilm stage infection, which causes long time. Purpose: determine...

Wounds expose a patient to serious hazards like wound infection, tissue destruction, disfiguring and disabling scars. Use of superoxidised solution (oxum) in infected wounds, ulcers, diabetic wounds, abcesses, burns reduced morbidity and hospital stay with its early wound healing effect. To evaluate the effect of superoxidised water (Oxum) V/s povidone iodine (Betadine) on similar types of woun...

BACKGROUND Many studies have demonstrated that honey has antibacterial activity in vitro, and a small number of clinical case studies have shown that application of honey to severely infected cutaneous wounds is capable of clearing infection from the wound and improving tissue healing. Research has also indicated that honey may possess anti-inflammatory activity and stimulate immune responses w...

Background Postoperative pyoderma gangrenosum (PPG) is a rare inflammatory skin disease of unknown etiology characterized by blistering and ulcerative lesions in postoperative wounds. Untreated (PG) potentially life-threatening; therefore, immediate appropriate treatment essential. Although PPG surgical site infection (SSI) present similar clinical findings, they should be differentiated becaus...

BACKGROUND Debridement is essential for successful wound management. Enzymatic debridement is commonly utilized in wound care but has been reported to be unsafe in wounds with significant bacterial bioburden, unless used in conjunction with topical antimicrobials. We examine this hypothesis with 2 commercially available, commonly used preparations of enzymatic debriding agents. MATERIALS AND ...