Multiple comparison procedures that control a family-wise error rate or false discovery rate provide an achieved error rate as the adjusted p-value or q-value for each hypothesis tested. However, since achieved error rates are not understood as probabilities that the null hypotheses are true, empirical Bayes methods have been employed to estimate such posterior probabilities, called local false...

Multiple hypothesis testing is a significant problem in nearly all neuroimaging studies. In order to correct for this phenomena, we require a reliable estimate of the Family-Wise Error Rate (FWER). The well known Bonferroni correction method, while being simple to implement, is quite conservative, and can substantially under-power a study because it ignores dependencies between test statistics....

post failure analysis of massive structure infers that soil-structure interaction (ssi) is a crucial phenomena influencing seismic response of massive structures. cable-stayed bridge’s popularity and numbers are increasing now-a-days because of economical longer span & aesthetic good look. the current paper examines the effect of depth of foundation on seismic response of cable-stayed bridg...

one of the most important sources of imamiyyah jurisprudence is the tradition in the form of reliable report. and a significant part of it, refers to external threads, but the renowned osuli's jurisprudents take the view that the scope of the reliable authority credit, is limited to injunctions and argue that account is a subject concerning with evidence chapter in which justice and witnes...

Intertidal mudflats are land-sea interaction areas and play important roles in global nutrient cycles. However, a comprehensive understanding of microbial communities in these mudflats remains elusive. In this study, mudflat sediment samples from the Dongtan wetland of Chongming Island, the largest alluvial island in the world, were collected. Using a modified metatranscriptomic method, the dep...

This paper proposes a boosting-based solution addressing metric learning problems for high-dimensional data. Distance measures have been used as natural measures of (dis)similarity and served as the foundation of various learning methods. The efficiency of distance-based learning methods heavily depends on the chosen distance metric. With increasing dimensionality and complexity of data, howeve...

Cellular interactions can be modeled as complex dynamical systems represented by weighted graphs. The functionality of such networks, including measures of robustness, reliability, performance, and efficiency, are intrinsically tied to the topology and geometry of the underlying graph. Utilizing recently proposed geometric notions of curvature on weighted graphs, we investigate the features of ...

Let κ be an uncountable regular cardinal. Call an equivalence relation on functions from κ into 2 Σ11-definable over H(κ) if there is a first order sentence φ and a parameter R ⊆ H(κ) such that functions f, g ∈ κ2 are equivalent iff for some h ∈ κ2, the structure 〈H(κ),∈, R, f, g, h〉 satisfies φ, where ∈, R, f , g, and h are interpretations of the symbols appearing in φ. All the values μ, 1 ≤ μ...