The impact of weight change on diabetes incidence remains unclear. To clarify the role of weight change as a risk factor for diabetes, the authors assessed the association between weight change and diabetes incidence conditional upon either initial or attained body mass index (BMI). They used 7,837 observations available from repeated measurements of 4,259 participants (men and women aged 20-59...

OBJECTIVE This project audited rate and extent of weight loss in a primary care/commercial weight management organisation partnership scheme. METHODS 34,271 patients were referred to Slimming World for 12 weekly sessions. Data were analysed using individual weekly weight records. RESULTS Average (SD) BMI change was -1.5 kg/m² (1.3), weight change -4.0 kg (3.7), percent weight change -4.0% (...

BACKGROUND Low body weight was one of the risk factors of osteoporosis. Little is known about the correlation between body weight change and bone mineral density (BMD) in Korean women. Therefore, this study was designed to reveal the impact of body weight change on BMD of the lumbar spine in perimenopausal women. METHODS 105 healthy perimenopausal women aged between 44 and 50 years old were e...

Spike timing plasticity (STDP) is a special form of synaptic plasticity where the relative timing of postand presynaptic activity determines the change of the synaptic weight. On the postsynaptic side, active backpropagating spikes in dendrites seem to play a crucial role in the induction of spike timing dependent plasticity. We argue that postsynaptically the temporal change of the membrane po...

BACKGROUND Parents are the key agents of behavioural changes in their children. This fact is as an important aspect of obesity treatment and prevention. The present study aims to evaluate the influence of parents who have gained or lost weight on their children's weights and to examine parental and child patterns of weight changes from a baseline over a 14-year duration. METHODS We performed ...

Objectives: This study investigates the longitudinal association between 5-year weight change and quality of life (QoL) in Dutch men and women. Subjects: 2,414 men and women from the Maastricht region of the Netherlands. Measurements: QoL outcomes were measured by the RAND-36 (eight subscales and two overall 5 composite scores, physical and mental health (PCS and MCS)). Weight was measured on a...