Abstract Maize lethal necrosis (MLN) is a devastating disease of maize caused by synergistic infection with chlorotic mottle virus (MCMV) and at least one potyvirid (e.g., sugarcane mosaic virus, SCMV). MLN results in leaf necrosis, premature aging, even whole plant death can cause up to 100% losses yield. has emerged worldwide resulted serious loss production. Over the past decade, extensive r...