نتایج جستجو برای: wasting

تعداد نتایج: 8562  

Journal: :Current Biology 2006
Brian P. Lazzaro Madeline R. Galac

Drosophila melanogaster infected with Mycobacterium marinum suffer metabolic wasting similar to that seen in humans suffering from tuberculosis. This wasting is linked to insulin signaling and hastens host death.

Journal: :The International Journal of Biochemistry & Cell Biology 2013

Journal: :Circulation: Heart Failure 2010

2015
Qi Yuan Thomas Eckland Glenn Telling Jason Bartz Shannon Bartelt-Hunt

Prions enter the environment from infected hosts, bind to a wide range of soil and soil minerals, and remain highly infectious. Environmental sources of prions almost certainly contribute to the transmission of chronic wasting disease in cervids and scrapie in sheep and goats. While much is known about the introduction of prions into the environment and their interaction with soil, relatively l...

Journal: :Ecological applications : a publication of the Ecological Society of America 2007
Mary M Conner Michael W Miller Michael R Ebinger Kenneth P Burnham

Advances in acquiring and analyzing the spatial attributes of data have greatly enhanced the potential utility of wildlife disease surveillance data for addressing problems of ecological or economic importance. We present an approach for using wildlife disease surveillance data to identify areas for (or of) intervention, to spatially delineate paired treatment and control areas, and then to ana...

2011
Chad J. Johnson Allen Herbst Camilo Duque-Velasquez Joshua P. Vanderloo Phil Bochsler Rick Chappell Debbie McKenzie

Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection. To test this effect, we orally inoculated 12 white-tailed deer with CWD agent. Three different PRNP alleles, wild-type (wt; glutamine at amino acid 95 and glycine at 96), Q95H (glutamine to histidine at amino acid position 9...

2014
Christopher S. Jennelle Viviane Henaux Gideon Wasserberg Bala Thiagarajan Robert E. Rolley Michael D. Samuel

Few studies have evaluated the rate of infection or mode of transmission for wildlife diseases, and the implications of alternative management strategies. We used hunter harvest data from 2002 to 2013 to investigate chronic wasting disease (CWD) infection rate and transmission modes, and address how alternative management approaches affect disease dynamics in a Wisconsin white-tailed deer popul...

Journal: :Journal of toxicology and environmental health. Part A 2011
Kip G Rogers Stacie J Robinson Michael D Samuel Daniel A Grear

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy affecting North American cervids. Because it is uniformly fatal, the disease is a major concern in the management of white-tailed deer populations. Management programs to control CWD require improved knowledge of deer interaction, movement, and population connectivity that could influence disease transmission and spread....

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Ian Hewson Jason B Button Brent M Gudenkauf Benjamin Miner Alisa L Newton Joseph K Gaydos Janna Wynne Cathy L Groves Gordon Hendler Michael Murray Steven Fradkin Mya Breitbart Elizabeth Fahsbender Kevin D Lafferty A Marm Kilpatrick C Melissa Miner Peter Raimondi Lesanna Lahner Carolyn S Friedman Stephen Daniels Martin Haulena Jeffrey Marliave Colleen A Burge Morgan E Eisenlord C Drew Harvell

Populations of at least 20 asteroid species on the Northeast Pacific Coast have recently experienced an extensive outbreak of sea-star (asteroid) wasting disease (SSWD). The disease leads to behavioral changes, lesions, loss of turgor, limb autotomy, and death characterized by rapid degradation ("melting"). Here, we present evidence from experimental challenge studies and field observations tha...

2004
Ermias D. Belay Ryan A. Maddox Elizabeth S. Williams Michael W. Miller Pierluigi Gambetti Lawrence B. Schonberger

Chronic wasting disease (CWD) of deer and elk is endemic in a tri-corner area of Colorado, Wyoming, and Nebraska, and new foci of CWD have been detected in other parts of the United States. Although detection in some areas may be related to increased surveillance, introduction of CWD due to translocation or natural migration of animals may account for some new foci of infection. Increasing spre...

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