is a typical story. a patient arrives at the emergency room. he was well when he went to bed and then he woke up with symptoms suggestive of stroke several hours later. even without further scrutiny, the clinician determines that intravenous thrombolytic therapy is contraindicated. end of story. Such is the plight of patients with wake-up stroke. Can we do more? Can we do better? Wake-up stroke...

Linear stability analysis of the three dimensional plane wake flow is performed using a mapped finite di?erence scheme in a domain which is doubly infinite in the cross–stream direction of wake flow. The physical domain in cross–stream direction is mapped to the computational domain using a cotangent mapping of the form y = ?cot(??). The Squire transformation [2], proposed by Squire, is also us...

Abstract. Floating offshore wind turbines may experience large surge motions, which can cause blade–vortex interaction if they are similar to or faster than the local speed. Previous research hypothesized that this phenomenon represented a turbulent wake state even vortex ring state, rendering actuator disc momentum theory and blade element invalid. This hypothesis is challenged, we show valid ...

Wake models play a fundamental role in predicting loads and power generated by wind farms. Using them, it is possible to assess how wakes develop interact with each other what are the effects context of real operating farm. In this paper, Gaussian Model implemented OpenFAST validated against experimental data gathered tunnel GVPM @ Politecnico di Milano European CL-Windcon project. The software...

the aerodynamics of road vehicles has frequently been studied in simplified geometries to separate the effect of various components on aerodynamic drag and on near wake flow dynamics. in this work, the characteristics of the near wake of a notch-back car model were investigated, using hot-wire anemometer. the main objectives of this study are to gain a better understanding of the flow structure...

INTRODUCTION Rodent sleep research uses electroencephalography (EEG) and electromyography (EMG) to determine the sleep state of an animal at any given time. EEG and EMG signals, typically sampled at >100 Hz, are segmented arbitrarily into epochs of equal duration (usually 2-10 seconds), and each epoch is scored as wake, slow-wave sleep (SWS), or rapid-eye-movement sleep (REMS), on the basis of ...

Sleep-wake schedule disorder is defined by DSM-III-R as a mismatch between the normal sleep-wake schedule for a person's environment and his or her circadian sleep-wake pattern. The authors report a case in which a sleep-wake schedule disorder arose after a closed head injury. Sleep-wake schedule disorder has not been described as an outcome of closed head injury. As patients with sleep-wake sc...

How the circadian clock regulates the timing of sleep is poorly understood. Here, we identify a Drosophila mutant, wide awake (wake), that exhibits a marked delay in sleep onset at dusk. Loss of WAKE in a set of arousal-promoting clock neurons, the large ventrolateral neurons (l-LNvs), impairs sleep onset. WAKE levels cycle, peaking near dusk, and the expression of WAKE in l-LNvs is Clock depen...

To analyze the ecological features of microbial quiescence, a model is proposed that involves "wake-up" rate and "sleep" rate at which the population transitions from a quiescent to an active state and back, respectively. These rates depend continuously on the resources and turn on and off at resource thresholds which may not coincide. The usual dichotomy is observed: the population is washed o...