Vulvar lymphangioma circumscriptum (LC) is a rare entity which may present as a painful, warty lesion. In contrast to the congenital form, which occurs in children, the acquired form arises in older adults and may be associated with infection, Crohn's disease, or prior pelvic/regional surgery. We present a case of acquired LC of the vulva in a 55-year-old woman who presented with a 3-4 year his...

PURPOSE To evaluate outcome and morbidity in patients with vulvar cancer treated with radiotherapy, concurrent chemoradiotherapy or postoperative radiotherapy. MATERIALS AND METHODS The records of 24 patients treated with radiotherapy for vulvar cancer between July 1993 and September 2009 were retrospectively reviewed. All patients received once daily 1.8-4 Gy fractions external beam radiothe...

Gabriella Lillsunde Larsson (2014): Characterization of HPV-induced vaginal and vulvar carcinoma. Örebro Studies in Medicine 112. Vaginal and vulvar carcinomas are rare gynaecological malignancies, partly caused by the human papilloma virus (HPV). HPV-16 is the most frequent genotype found and HPV as a prognostic factor for these women has not been fully investigated. A persistent HPV-infection...

Cigarette smoking is an established cofactor to human papillomavirus (HPV) in the development of cervical and vulvar squamous cell carcinoma (SCC), and may influence risk through an immunosuppressive pathway. Genetic variation in interleukin 2 (IL2), associated in some studies with the inhibition of HPV-targeted immunity, may modify the effect of smoking on the risk of HPV-related anogenital ca...

Although the physiological characteristics of vulvar skin have been characterized in Caucasians, little is known about the vulvar skin of Asian women. This study assessed the moisture content, transepidermal water loss (TEWL) and pH of vulvar skin of 99 healthy Asian women residing in Bangkok, aged 20-69 years, during their non-menstrual period, including 39 post-menopausal women. Skin pH was a...

The development of Squamous Cell Carcinoma (SCC) is a severe complication of chronic Hidradenitis Suppurativa (HS). Male patients with prolonged HS in extra-axillary areas are especially at risk of this complication. The case in our paper of HS associated with vulvar SCC emphasizes that women can also develop this complication. In addition to lichen sclerosus vulvae (via dVIN) and high risk HPV...

BACKGROUND Although postmenopausal vulvar pain is frequently attributed to vaginal atrophy, such symptoms may be due to vulvodynia, a chronic vulvar pain condition. Given the limited research on vulvodynia in postmenopausal women, the objective of this study was to provide preliminary population-based data on the associations of vaginal symptoms, serum hormone levels and hormone use with chroni...

schwannoma is a solitary, slow growing,  benign tumour of the peripheral  nerve sheath, and it is most common locations are the head, neck, the flexor surfaces of the extremities, retroperitoneal and posterior mediastinium. external female genital organs are the least common location site of the schwannoma. only a few cases of vulvar schwannoma have been reported.we report 65 year- old woman pr...

BACKGROUND Women with node-positive vulvar cancer have a high risk for disease recurrence. Indication criteria for adjuvant radiotherapy are controversial. This study was designed to further understand the role of adjuvant therapy in node-positive disease. METHODS Patients with primary squamous-cell vulvar cancer treated at 29 gynecologic cancer centers in Germany from 1998 through 2008 were ...