Harms of drugs are an important cause of mortality and morbidity. The use of pharmaceuticals always entails a risk of adverse events, often to an unknown extent, and increased drug utilization has made drug-related problems a common occurrence (1). It is, for instance, estimated that adverse drug reactions (ADRs) cause the European Union almost 200,000 deaths annually (2) and cost approximately...

This study investigates the quality of Integrated Report (IR) in voluntary and compulsory setting. study's first objective is to measure IR disclosure assess whether companies comply with 2013 framework. The second examine there any difference reporting between IR's regime regime. A sample 120 international listed on International Reporting Council (IIRC) websites throughout three years (2014-2...

Adverse drug reactions (ADRs) are considered as one of the leading causes of death among hospitalized patients. Thus reporting of adverse drug reactions become an important phenomenon. Spontaneous adverse drug reaction reporting form is an essential component and a major tool of the pharmacovigilance system of any country. This form is a tool to collect information of ADRs which helps in establ...

Objective We aimed at testing if a correlation between adverse drug reactions relative risks estimated from meta-analyses and disproportionality analyses calculated pharmacovigilance spontaneous reporting systems databases exist, methodological choices modify this correlation. Study design extracted (ADR) odds ratios (ORs) used as reference corresponding Reporting Odds Ratios (RORs) the WHO dat...

Adverse drug reactions (ADRs) are unwanted drug effects that have considerable economic as well as clinical costs as they often lead to hospital admission, prolongation of hospital stay and emergency department visits. Randomized controlled trials (RCTs) are the main premarketing methods used to detect and quantify ADRs but these have several limitations, such as limited study sample size and l...

Contact me when new articles are published in these topic areas. A DVERSE DRUG AND DEVICE REactions (ADRs) account for as many as 100 000 deaths annually. 1 Prior to US Food and Drug Administration (FDA) approval, drugs are evaluated in well-designed and carefully monitored clinical trials. Only half of newly discovered serious ADRs are detected and documented in the Phy-sicians' Desk Reference...

Background: Voluntary hospital reporting systems are potentially valuable sources of information about medical errors and adverse events. This study examined the extent and variation in the reporting of medication errors and adverse drug events in a voluntary hospital incident reporting system. Methods: A retrospective analysis of received incident reports of potential and preventable adverse d...

OBJECTIVES The present study was undertaken to provide the health professionals who were working at a tertiary care hospital, with a simple method to report Adverse Drug Reactions (ADRs) and to monitor, document and to evaluate them according to the set criteria. METHOD AND MATERIALS This study was conducted over a period of 15 months from 1st Jan' 2008 to 31st March 2009 at Goa Medical Colle...

The musculoskeletal system can be a target organ for adverse drug reactions (ADRs). Drug-induced muscle, bone or connective tissue injuries may be due to, i), primary direct drug action, or, ii), undirected consequence of generalized drug-induced disease. Musculoskeletal ADRs may be only temporarily disabling, such as muscle cramps, as well as in other cases may be serious and life-threatening,...