The present research was conducted to find out acaricidal efficacy of methanolic extracts Calotropis gigantea against Rhipicephalus (Boophilus) microplus ticks in Udaipur (Rajasthan). Larval packet Test (LPT) and Adult Immersion (AIT) were used evaluate efficacy. A total four concentrations the extract (12.5%, 25%, 50%, 100%) along with one control group twice replications for each concentratio...

The goals of the current studies were to create herbal excipients-based ketoconazole cream enhance efficacy against chronic mucocutaneous candidiasis. Ketoconazole, coconut oil and other excipients namely shea butter, bees wax, Lanolin Rose used for formulation. Each formulation was prepared with various concentrations oil. Every formulations evaluated successfully. Among all F4 best that exhib...

Monoclonal antibodies targeting tumors are one of the most important discoveries in field cancer. Although several effective have been developed, a relapse may occur. One their mechanisms action is Antibody Dependent Cell Cytotoxicity (ADCC), by engaging Fc γ receptor CD16 expressing Natural Killer cells, innate lymphoid cells involved cancer immunosurveillance and able to kill tumor cells. A l...

Abstract Natural products are major molecules for drug discovery due to their structural diversity and interaction with various biological targets, yet clinical application is limited by poor water solubility or low lipophilicity, inappropriate molecular size, dissolution rate permeation, instability, high metabolic rapid clearance. These issues can be solved nanomedicine, improving bioavailabi...

Osteoarthritis (OA) is affecting large proportions of the population worldwide. So far, no effective disease modifying drug has been developed for this disease, limiting therapeutic options to pain medications, physiotherapy and ultimately surgical approaches, mainly joint implant surgery. In vitro animal studies have demonstrated that bisphosphonates potential become modalities treatment OA. T...

a study was conducted to investigate the effect of follicular size (small,

Dual-acting kappa opioid receptor (KOR) agonist and mu opioid receptor (MOR) partial agonist ligands have been put forward as potential treatment agents for cocaine and other psychostimulant abuse. Members of the orvinol series of ligands are known for their high binding affinity to both KOR and MOR, but efficacy at the individual receptors has not been thoroughly evaluated. In this study, it i...

Sedentarism is a serious health concern in industrialized countries throughout the world. We examined whether a text message-based intervention, targeted at increasing daily levels of physical activity, would be more effective than a standard psychoeducational intervention and a control condition. Sixty-three individuals (43 women) with a mean age of 23.7 years participated in the study. They w...

AIM This study examined the relationships between health literacy, self-efficacy and preventive care utilization among older adults in Taiwan. METHODS The data were from a longitudinal survey, "Taiwan Longitudinal Study in Aging" in 2003 and 2007. A total of 3479 participants who completed both two waves were included for analysis. Health literacy first was constructed through education, cogn...

Depression in prepubertal age group is a relatively rare condition. The presence of life threatening catatonic features call for aggressive treatment. Electro convulsive therapy (ECT) has been described to be effective in these circumstances; however, doubts have been raised about its safety profile. This present case study illustrates the efficacy and safety of ECT in prepubertal catatonia.