Various efforts have been made in past in order to predict the underlying mechanism of pesticide-induced toxicity using in vitro and animal models, however, these predictions may or may not be directly correlated with humans. The present study was designed to investigate the carbofuran induced genotoxicity and its amelioration by vitamins C and E by treating human peripheral blood lymphocytes (...

Caffeine (1,3,7-trimethylxanthine) is an habitual substance present in a wide variety of beverages and in chocolate-based foods and it is also used as adjuvant in some drugs. The antioxidant ability of caffeine has been reported in contrast with its pro- oxidant effects derived from its action mechanism such as the systemic release of catecholamines. The aim of this work was to evaluate the eff...

Rose Bengal photosensitized flow injection chemiluminescence method is reported using luminol-Cu(II) for the determination of vitamins A and C in pharmaceutical formulations. The reaction is based on the enhancement effect of analyte in the production of anion radicals of Rose Bengal (RB (•-)) which rapidly interact with dissolved oxygen and generate superoxide anions radicals (O2 (•-)) and hyd...

Some of the early studies on the vitamin content of dried fruits and vegetables are open to the objection that the products studied either were not commercial or were dried under conditions that affect adversely many qualities other than vitamins of the products. This report covers a part of an investigation undertaken cooperatively by the two laboratories involved, and intended to show t,he ef...

Harris and Ray (1935) reported that 11.74 to 38.1 mg of vitamin C was excreted in urine per day in healthy European subjects. Mosl of the Indian Workers have noted a lower output. Chakraborty and Roy obtai:led an average of 9.65 mg vitamin C excretion per day in two subjects. Ranganathan and Sankaran(1937) found low figure of7.6 to 9.4 mg per day in four adults, and 10.8 to 27.0 mg in 5 Sikh an...

Seventeen months' supplementation of the diet with vitamin C in elderly residents in an old persons' home failed to show any changes in sublingual lesions, which on histological examination proved to be aneurysmal dilatations of the venules. Nine months' supplementation of 40 to 80 mg. daily of vitamin C was necessary before the white-cell vitamin levels reached that found in younger people. Th...

To establish the most convenient and effective method to dry tangerine peels, different methods (sun drying, hot-air drying, freeze drying, vacuum drying, and medium- and short-wave infrared drying) were exploited. Our results indicated that medium- and short-wave infrared drying was the best method to preserve nutraceutical components; for example, vitamin C was raised to 6.77 mg/g (D.W.) from...

T he polarization of views on vitamin • C that has occurred in the last few years is well illustrated by the following sequence of events: 1970, Linus Pauling's book, "Vitamin C and the Common Cold” was published and became a bestseller, 1972, Irwin Stone published "The Healing Factor: Vitamin C Against Disease/' claiming a wide variety of health benefits from large doses of Vitamin C. 1974, th...

Scurvy is a potentially lethal condition caused by inadequate vitamin C intake. Hypovitaminosis of vitamin C causes vessel fragility and follicular hyperkeratosis that can lead to palpable purpuric skin lesions. In this case report, we aim to remind readers that scurvy still occurs in Western countries and that the clinical presentation may resemble vasculitis.

Obituary: COOPER and PROFESSOR R. A. BRINK, On the Obituary: Localization of Enzymes in Nerve Fibers: DRs. D. Alexander Lowy: DR. ALEXANDER SILVERMAN. NACHMANSOHN and H. B. STEINBACH .............................. 75 Orin F. Stafford: DR. F. L. SHINN. Recent Deaths 62 Scientific Events: Scientific Apparatus and Laboratory Methods: War Work of the Canadian Research Council; The A Color Reaction ...