The quantification of viral nucleic acids in serum by real-time PCR plays an important role in diagnosing hepatitis B virus and hepatitis C virus infection. In this study, we developed an assay using specific primers and probes to quantify hepatitis B virus DNA or hepatitis C virus RNA in serum from infected patients. For standardization and validation of the assay, an international panel of he...

In May 2016, at the World Health Assembly, 194 governments adopted the first-ever Global Health Sector Strategy on viral hepatitis and agreed to the first-ever global targets. The strategy includes a target to treat 8 million people for hepatitis B or C by 2020. The longer term aim is to reduce new viral hepatitis infections by 90% and to reduce the number of deaths due to viral hepatitis by 65...

In May 2016, at the World Health Assembly, 194 governments adopted the first-ever Global Health Sector Strategy on viral hepatitis and agreed to the first-ever global targets. The strategy includes a target to treat 8 million people for hepatitis B or C by 2020. The longer term aim is to reduce new viral hepatitis infections by 90% and to reduce the number of deaths due to viral hepatitis by 65...

Pregnant women with acute viral hepatitis are at higher risk of morbidity and death than pregnant women with chronic viral hepatitis. The risk of death is highest with acute viral hepatitis E, and the rate of transmission to the baby may be highest with hepatitis B virus (HBV) infection. Managing viral hepatitis in pregnancy requires assessing the risk of transmission to the baby, determining t...

â  â  hepatocellular carcinoma (hcc) is a major worldwide public health concern. despite recent advances, there has been little success in improving the survival of hcc patients. due to advances in diagnostic modalities and the increasing incidence of chronic viral hepatitis and nonalcoholic fatty liver disease (nafld), both of which are well known risk factors of hcc, the prevalence of hcc is ...

conclusions according to the presented case and subsequent literature review on fatal ebv hepatitis, clinicians should consider ebv infection in the differential diagnosis when hepatitis occurs in critically ill patients during the anti-tb therapy. although hepatitis caused by ebv is mostly self-limited, some might be fetal. introduction although hepatitis is frequently observed during antitube...

Background. Hepatitis B is an important public health issue in endemic areas, especially with the HIV epidemic. In the USA, hepatitis B and HIV coinfection represent approximately 6-10% of people living with HIV/AIDS. We report the experience with HIV-Hepatitis B-coinfected patients in our clinic Methods. Of 1011 na•ve HIV patients enrolled at IDP from June 2004 to December 2011 who had availab...

NL Biotechnologies is a biotech R&D company that specializes in viral Hepatitis B, C, and E vaccine development. The proprietary recombinant Hepatitis B vaccine technology has been commercialized in 2002 by Instituto Butantan (Brazil) and in 2004 by Probiomed S.A. de C.V. (Mexico). The overall sales exceed 200 million doses. Since 2001, NL Biotechnologies in collaboration with CDC (US, Atlanta)...

Introduction: Chronic hepatitis C and hepatitis B virus infections are pandemic affecting more than 170 million and 2 billion people worldwide, respectively. These infections can lead to cirrhosis, hepatocellular carcinoma, and extra hepatic complications like type 2 diabetes mellitus. In this study, we assessed the association of chronic hepatitis C and B virus infections with diabetes mellitu...

The variability of the clinical course in viral hepatitis depends more on the immune response of the host that on the type of virus involved. Inductors/helpers (LT4) or cytotoxic/suppressors (LT8) T-lymphocytes regulate the immune response which can be modified during infection or in homosexuals who are at high risk for viral infection. We studied 45 males with viral hepatitis (25 B, 13 A, and ...