The apoptotic process in the normal gastrointestinal mucosa is of interest due to its possible role in physiological cell renewal. The aim of this study was to identify the apoptotic process in the monkey small intestine and the association of glutathione level and its efflux in this process. Monkey small intestinal epithelial cells were separated in to different fractions consisting of villus,...

All cells in the intestinal villus of the rat are capable of synthesizing protein from amino acid precursors (l-leucine). Moreover, polyribosomes from both crypts and villi are equally able to incorporate l-leucine into protein. Unlike other tissues, e.g. liver, there is no diurnal variation of protein synthesis in the intestine of the unfed rat, whether leucine is administered intraluminally o...

Cellular retinol-binding protein type II (CRBPII) is exclusively expressed in the small intestinal absorptive cells. We previously reported that dietary fat induces CRBPII expression within 12 h of fat intake. To examine at which locus of the villus-crypt axis this response to dietary fat occurs, 6-wk-old rats were fed a low-fat diet (7% energy) for 7 d, and then given free access to a high-fat...

It has been shown that during the early phase of lactation porcine milk contains high concentrations of hormones and growth factors. The aim of the present investigation was to examine the hypothesis that the temporal coordination of intestinal maturation in piglets can be extrinsically regulated through changes in the composition of milk during the suckling period. Gut morphology and the ontog...

This study was conducted to test the effects of supplemental L-Met on redox status, gut development, and growth performance of young broiler chickens compared with DL-Met. A total of 888 (half male and half female) 1-d-old Ross 308 chickens were weighed and randomly allotted to 7 treatments in a randomized complete block design for 21 d, including a basal diet (BD), the BD + 0.095% L-Met or DL-...

This study investigated the protective effect of β-1,3/1,6-glucan on gut morphology, intestinal epithelial tight junctions, and bacterial translocation of broiler chickens challenged with Salmonella enterica serovar Typhimurium. Ninety Salmonella-free Arbor Acre male broiler chickens were randomly divided into 3 groups: negative control group (NC), Salmonella Typhimurium-infected positive group...

Chorionic villus sampling (CVS) is a test used for prenatal diagnosis [5]. Safe to perform at an earlier stage in pregnancy [6] than amniocentesis, CVS is another invasive prenatal diagnostic test that can be performed as early as ten weeks after the woman?s last menstrual cycle. While this test does carry some risks, it is generally very effective at predicting heritable diseases during or soo...

Chorionic villus sampling (CVS) is a test used for prenatal diagnosis [5]. Safe to perform at an earlier stage in pregnancy [6] than amniocentesis, CVS is another invasive prenatal diagnostic test that can be performed as early as ten weeks after the woman?s last menstrual cycle. While this test does carry some risks, it is generally very effective at predicting heritable diseases during or soo...

Chorionic villus sampling (CVS) is a test used for prenatal diagnosis [5]. Safe to perform at an earlier stage in pregnancy [6] than amniocentesis, CVS is another invasive prenatal diagnostic test that can be performed as early as ten weeks after the woman?s last menstrual cycle. While this test does carry some risks, it is generally very effective at predicting heritable diseases during or soo...

BACKGROUND Environmental enteric dysfunction (EED) is widespread throughout the tropics and in children is associated with stunting and other adverse health outcomes. One of the hallmarks of EED is villus damage. In children with severe acute malnutrition (SAM) the severity of enteropathy is greater and short term mortality is high, but the metabolic consequences of enteropathy are unknown. Her...