Factor VII activity (FVIIc), a risk marker for coronary heart disease, is increased during postprandial lipemia. Factor VII activation accompanies lipolysis of triglyceride-rich lipoproteins, but the nature of this association and whether it is causal remain uncertain. To explore this issue, four patients with homozygous factor XII deficiency, four with complete factor XI deficiency, six with f...

Pertechnetate, (99)Tc(VII)O(4)(-), is a highly mobile radionuclide contaminant at US Department of Energy sites that can be enzymatically reduced by a range of anaerobic and facultatively anaerobic microorganisms, including Shewanella oneidensis MR-1, to poorly soluble Tc(IV)O(2(s)). In other microorganisms, Tc(VII)O(4)(-) reduction is generally considered to be catalysed by hydrogenase. Here, ...

Lysosomal storage disorders constitute a large group of genetic diseases, many of which are characterized by mental retardation and other neurologic symptoms. The mechanisms of neural dysfunction remain poorly understood. Because neural progenitor cells (NPCs) are fundamentally important to normal brain development and function, we investigated NPC properties in a canine model of mucopolysaccha...

Bretaudiere J. Factor VII gene intronic mutation in a lethal Factor VII deficiency: effects on splice-site selection. Blood 2003; 102: 561–3. 10 Rosen E, Chan JCY, Idusogie E, Clotman F, Vlasuk G, Luther T, Jalbert LR, Albrecht S, Zhong L, Lissens A, Schoonjans L, Collen D, Costellino FJ, Carmeliet P. Mice lacking Factor VII develop normally but suffer fatal perinatal bleeding. Nature 1997; 390...

iv Acknowledgements v List of Tables vii List of Graphs vii

....................................................................................................iii-iv Acknowledgements............................................................................................v List of Tables.................................................................................................vii List of Figures.....................................................

Since 1979, the Health Resources and Services Administration, Bureau of Health Professionals Title VII, Section 747 (Title VII) programs have been critical to both fellowship and leadership training in academic general pediatrics. Title VII-funded faculty development programs and targeted contract funding have played an important role in training pediatric academic generalist faculty, supportin...

................................................................................................................................... i ACKNOWLEDGMENTS ........................................................................................................... iv VITA.......................................................................................................................................

............................................................................................................................ iv ACKNOWLEDGMENTS........................................................................................................vi LIST OF TABLES ..................................................................................................................vii LIST OF FIGURE...

.......................................................................................................... ii LIST OF FIGURES............................................................................................... vi LIST OF TABLES .................................................................................................vii ACKNOWLEDGEMENTS............................................